A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development.

A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development.

<h4>Background</h4>The PARP family member poly(ADP-ribose) polymerase 3 (PARP3) is structurally related to the well characterized PARP1 that orchestrates cellular responses to DNA strand breaks and cell death by the synthesis of poly(ADP-ribose). In contrast to PARP1 and PARP2, the funct...

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Main Authors: Michèle Rouleau, Vishal Saxena, Amélie Rodrigue, Eric R Paquet, Abbie Gagnon, Michael J Hendzel, Jean-Yves Masson, Marc Ekker, Guy G Poirier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0015834&type=printable
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