A Late-Diagnosed Case of Common Variable Immunodeficiency
Common Variable Immunodeficiency (CVID) is the most common form of primary immunodeficiency (PID). CVID is characterized by decreased serum immunoglobulin levels, decreased or absent antibody production, and normal or low B-lymphocyte counts. It has a wide variety of clinical presentations, includin...
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Kirsehir Ahi Evran University
2025-04-01
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| Series: | Ahi Evran Medical Journal |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/4268000 |
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| author | Coşkun Doğan Nurhan Kasap Cihan Örçen |
| author_facet | Coşkun Doğan Nurhan Kasap Cihan Örçen |
| author_sort | Coşkun Doğan |
| collection | DOAJ |
| description | Common Variable Immunodeficiency (CVID) is the most common form of primary immunodeficiency (PID). CVID is characterized by decreased serum immunoglobulin levels, decreased or absent antibody production, and normal or low B-lymphocyte counts. It has a wide variety of clinical presentations, including recurring infections, inflammatory diseases, gastrointestinal diseases, lymphoid hyperplasia, granulomatous diseases, cytopenias, progressive lung diseases, and non-communicable diseases such as cancer. The main treatments are antibiotic prophylaxis and immunoglobulin replacement therapy. In this case report, a 62-year-old patient with a medical history of pneumonia that had recurred at least six times in the last five years, one of which required hospitalization, a history of pulmonary thromboembolism, and a 10-day intensive care unite stay, lymphoproliferation, and a diagnosis of CVID as a result of further examinations is presented. |
| format | Article |
| id | doaj-art-e724f6748fd14af3b67900934b36ac27 |
| institution | OA Journals |
| issn | 2619-9203 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Kirsehir Ahi Evran University |
| record_format | Article |
| series | Ahi Evran Medical Journal |
| spelling | doaj-art-e724f6748fd14af3b67900934b36ac272025-08-20T02:14:27ZengKirsehir Ahi Evran UniversityAhi Evran Medical Journal2619-92032025-04-019112212710.46332/aemj.1562436A Late-Diagnosed Case of Common Variable ImmunodeficiencyCoşkun Doğan0https://orcid.org/0000-0002-6948-5187Nurhan Kasap1https://orcid.org/0000-0001-5432-4076Cihan Örçen2https://orcid.org/0000-0003-1047-2004STANBUL MEDENİYET ÜNİVERSİTESİ, TIP FAKÜLTESİİstanbul Medeniyet Üniversitesi Tıp Fakültesi Pediatrik İmmünoloji ve Allerji Bilim Dalı, İstanbul Türkiyeİstanbul Medeniyet Üniversitesi Tıp Fakültesi İmmünoloji ve Allerji Bilim Dalı, İstanbul TürkiyeCommon Variable Immunodeficiency (CVID) is the most common form of primary immunodeficiency (PID). CVID is characterized by decreased serum immunoglobulin levels, decreased or absent antibody production, and normal or low B-lymphocyte counts. It has a wide variety of clinical presentations, including recurring infections, inflammatory diseases, gastrointestinal diseases, lymphoid hyperplasia, granulomatous diseases, cytopenias, progressive lung diseases, and non-communicable diseases such as cancer. The main treatments are antibiotic prophylaxis and immunoglobulin replacement therapy. In this case report, a 62-year-old patient with a medical history of pneumonia that had recurred at least six times in the last five years, one of which required hospitalization, a history of pulmonary thromboembolism, and a 10-day intensive care unite stay, lymphoproliferation, and a diagnosis of CVID as a result of further examinations is presented.https://dergipark.org.tr/tr/download/article-file/4268000hypogammaglobulinemiaımmunoglobulin deficiencyımmune system diseasesprimary immunodeficiencyrecurrent pneumonia |
| spellingShingle | Coşkun Doğan Nurhan Kasap Cihan Örçen A Late-Diagnosed Case of Common Variable Immunodeficiency Ahi Evran Medical Journal hypogammaglobulinemia ımmunoglobulin deficiency ımmune system diseases primary immunodeficiency recurrent pneumonia |
| title | A Late-Diagnosed Case of Common Variable Immunodeficiency |
| title_full | A Late-Diagnosed Case of Common Variable Immunodeficiency |
| title_fullStr | A Late-Diagnosed Case of Common Variable Immunodeficiency |
| title_full_unstemmed | A Late-Diagnosed Case of Common Variable Immunodeficiency |
| title_short | A Late-Diagnosed Case of Common Variable Immunodeficiency |
| title_sort | late diagnosed case of common variable immunodeficiency |
| topic | hypogammaglobulinemia ımmunoglobulin deficiency ımmune system diseases primary immunodeficiency recurrent pneumonia |
| url | https://dergipark.org.tr/tr/download/article-file/4268000 |
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