Validating LENT score in malignant pleural effusion

Aim: LENT score was developed to predict survival in malignant pleural effusion (MPE), this study aims to validate this score. Objectives: Validate LENT Prognostic Score for MPE and explore survival in these patients. Methods: Retrospective analysis of 202 patients who had MPE and received drainage...

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Main Authors: Alia Alawneh, Fadi Abu Farsakh, Mahmoud Smadi, Shaher Samrah
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Future Science OA
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Online Access:https://www.tandfonline.com/doi/10.2144/fsoa-2023-0168
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author Alia Alawneh
Fadi Abu Farsakh
Mahmoud Smadi
Shaher Samrah
author_facet Alia Alawneh
Fadi Abu Farsakh
Mahmoud Smadi
Shaher Samrah
author_sort Alia Alawneh
collection DOAJ
description Aim: LENT score was developed to predict survival in malignant pleural effusion (MPE), this study aims to validate this score. Objectives: Validate LENT Prognostic Score for MPE and explore survival in these patients. Methods: Retrospective analysis of 202 patients who had MPE and received drainage between January 2013 and June 2015. Results: Median survival was 2.98 months. Patients were classified according to LENT score as low, moderate and high-risk groups: 5 (4.2%), 61 (50.8%), and 54 (45%), respectively. Kaplan–Meier curve showed median survival for each group: 9.41, 5.36 and 0.56 months, respectively, p-values <0.001. AUC for 1, 3 and 6 months: 0.741, 0.781, 0.790, respectively, p-values <0.001. Conclusion: LENT score is valid for predicting survival in patients with MPE.
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spelling doaj-art-e7201bbecc9b4f4b95a1c568a800cd062025-08-20T02:41:39ZengTaylor & Francis GroupFuture Science OA2056-56232024-12-0110110.2144/fsoa-2023-0168Validating LENT score in malignant pleural effusionAlia Alawneh0Fadi Abu Farsakh1Mahmoud Smadi2Shaher Samrah3Jordan University of Science &amp; Technology, Faculty of Medicine, Internal Medicine Department, 3030, Ar-Ramtha, JordanKing Hussein Cancer Center, Palliative Medicine Department, Queen Rania St 202, Amman, JordanJordan University of Science &amp; Technology, Faculty of Science, Mathematics Department, 3030, Ar-Ramtha, JordanJordan University of Science &amp; Technology, Faculty of Medicine, Internal Medicine Department, Pulmonary &amp; Critical Care Division, 3030, Ar-Ramtha, JordanAim: LENT score was developed to predict survival in malignant pleural effusion (MPE), this study aims to validate this score. Objectives: Validate LENT Prognostic Score for MPE and explore survival in these patients. Methods: Retrospective analysis of 202 patients who had MPE and received drainage between January 2013 and June 2015. Results: Median survival was 2.98 months. Patients were classified according to LENT score as low, moderate and high-risk groups: 5 (4.2%), 61 (50.8%), and 54 (45%), respectively. Kaplan–Meier curve showed median survival for each group: 9.41, 5.36 and 0.56 months, respectively, p-values <0.001. AUC for 1, 3 and 6 months: 0.741, 0.781, 0.790, respectively, p-values <0.001. Conclusion: LENT score is valid for predicting survival in patients with MPE.https://www.tandfonline.com/doi/10.2144/fsoa-2023-0168LENT scoremalignancypleural effusionprognosisvalidation
spellingShingle Alia Alawneh
Fadi Abu Farsakh
Mahmoud Smadi
Shaher Samrah
Validating LENT score in malignant pleural effusion
Future Science OA
LENT score
malignancy
pleural effusion
prognosis
validation
title Validating LENT score in malignant pleural effusion
title_full Validating LENT score in malignant pleural effusion
title_fullStr Validating LENT score in malignant pleural effusion
title_full_unstemmed Validating LENT score in malignant pleural effusion
title_short Validating LENT score in malignant pleural effusion
title_sort validating lent score in malignant pleural effusion
topic LENT score
malignancy
pleural effusion
prognosis
validation
url https://www.tandfonline.com/doi/10.2144/fsoa-2023-0168
work_keys_str_mv AT aliaalawneh validatinglentscoreinmalignantpleuraleffusion
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AT mahmoudsmadi validatinglentscoreinmalignantpleuraleffusion
AT shahersamrah validatinglentscoreinmalignantpleuraleffusion