Lysosomal Stress in Cardiovascular Diseases: Therapeutic Potential of Cardiovascular Drugs and Future Directions
Lysosomal dysfunction has emerged as a central contributor to the pathogenesis of cardiovascular diseases (CVDs), particularly due to its involvement in chronic inflammation, lipid dysregulation, and oxidative stress. This review highlights the multifaceted roles of lysosomes in CVD pathophysiology,...
Saved in:
| Main Authors: | Toshiki Otoda, Ken-ichi Aihara, Tadateru Takayama |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-04-01
|
| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/13/5/1053 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Cadmium targeting transcription factor EB to inhibit autophagy-lysosome function contributes to acute kidney injury
by: Peng-Fei Dong, et al.
Published: (2025-06-01) -
Transcription factor EB improves hypoxic pulmonary hypertension in fetal rats by suppressing NLRP3 inflammasome activation via induction of mitophagy
by: Chaohong Chen, et al.
Published: (2025-07-01) -
c-Abl/TFEB Pathway Activation as a Common Pathogenic Mechanism in Lysosomal Storage Diseases: Therapeutic Potential of c-Abl Inhibitors
by: Miguel V. Guerra, et al.
Published: (2025-05-01) -
Pyroptosis as a therapeutic target in preeclampsia: current research and future directions
by: Yongchun Zhu, et al.
Published: (2025-06-01) -
Dual Role of Lysosome in Cancer Development and Progression
by: Xiao-Qiong Chen, et al.
Published: (2024-11-01)