Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysis

Introduction Cognitive–behavioural therapy (CBT) consists of multiple treatment techniques for each treatment model and is tailored to the patient’s characteristics. Randomised controlled trials (RCTs) have reported that CBT is effective for attention-deficit/hyperactivity disorder (ADHD); however,...

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Main Authors: Sayo Hamatani, Kazuki Matsumoto, Yoshihiko Kunisato, Sho Okawa, Masatoshi Yamashita, Yoshifumi Mizuno
Format: Article
Language:English
Published: BMJ Publishing Group 2023-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/4/e068547.full
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author Sayo Hamatani
Kazuki Matsumoto
Yoshihiko Kunisato
Sho Okawa
Masatoshi Yamashita
Yoshifumi Mizuno
author_facet Sayo Hamatani
Kazuki Matsumoto
Yoshihiko Kunisato
Sho Okawa
Masatoshi Yamashita
Yoshifumi Mizuno
author_sort Sayo Hamatani
collection DOAJ
description Introduction Cognitive–behavioural therapy (CBT) consists of multiple treatment techniques for each treatment model and is tailored to the patient’s characteristics. Randomised controlled trials (RCTs) have reported that CBT is effective for attention-deficit/hyperactivity disorder (ADHD); however, which CBT components are effective is unknown. In order to provide the best treatment technique, it is important to know which therapeutic component or combination thereof is more effective and what the specific effect size is.Methods and analysis We will perform component network meta-analysis (cNMA). The search will include studies published from database inception up to 31 March 2022, in English. The electronic databases of MEDLINE (via PubMed), EMBASE, PsycINFO, ClinicalTrials.gov and Cochrane Library will be searched. We will systematically identify all RCTs in the treatment of ADHD between the ages of 10 and 60 years, comparing interventions composed of various CBT components with controlled interventions. We will perform pairwise and network meta-analysis with random effects to estimate summary ORs and standardised mean differences. We will assess the risk of bias in selected studies using the Cochrane risk of bias tool.Ethics and dissemination Since we will review published papers, ethical approval is not required. The results from this cNMA will provide a panorama of the CBT-based ADHD studies. The results of this study will be published in a peer-reviewed journal.PROSPERO registration number CRD42022323898.
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spelling doaj-art-e7148a6f3cd041eca3c65df0546b25532025-08-20T02:12:29ZengBMJ Publishing GroupBMJ Open2044-60552023-04-0113410.1136/bmjopen-2022-068547Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysisSayo Hamatani0Kazuki Matsumoto1Yoshihiko Kunisato2Sho Okawa3Masatoshi Yamashita4Yoshifumi Mizuno52 United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Osaka, JapanDivision of Clinical Psychology, Kagoshima University Hospital, Kagoshima, JapanDepartment of Psychology, Senshu University, Kawasaki, JapanDepartment of Experimental Psychology, University of Oxford, Oxford, UK1 Research Centre for Child Mental Development, University of Fukui, Fukui, Japan1 Research Centre for Child Mental Development, University of Fukui, Fukui, JapanIntroduction Cognitive–behavioural therapy (CBT) consists of multiple treatment techniques for each treatment model and is tailored to the patient’s characteristics. Randomised controlled trials (RCTs) have reported that CBT is effective for attention-deficit/hyperactivity disorder (ADHD); however, which CBT components are effective is unknown. In order to provide the best treatment technique, it is important to know which therapeutic component or combination thereof is more effective and what the specific effect size is.Methods and analysis We will perform component network meta-analysis (cNMA). The search will include studies published from database inception up to 31 March 2022, in English. The electronic databases of MEDLINE (via PubMed), EMBASE, PsycINFO, ClinicalTrials.gov and Cochrane Library will be searched. We will systematically identify all RCTs in the treatment of ADHD between the ages of 10 and 60 years, comparing interventions composed of various CBT components with controlled interventions. We will perform pairwise and network meta-analysis with random effects to estimate summary ORs and standardised mean differences. We will assess the risk of bias in selected studies using the Cochrane risk of bias tool.Ethics and dissemination Since we will review published papers, ethical approval is not required. The results from this cNMA will provide a panorama of the CBT-based ADHD studies. The results of this study will be published in a peer-reviewed journal.PROSPERO registration number CRD42022323898.https://bmjopen.bmj.com/content/13/4/e068547.full
spellingShingle Sayo Hamatani
Kazuki Matsumoto
Yoshihiko Kunisato
Sho Okawa
Masatoshi Yamashita
Yoshifumi Mizuno
Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysis
BMJ Open
title Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysis
title_full Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysis
title_fullStr Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysis
title_full_unstemmed Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysis
title_short Dismantling cognitive–behavioural therapy components for attention-deficit hyperactivity disorder in adolescents and adults: protocol for a network meta-analysis
title_sort dismantling cognitive behavioural therapy components for attention deficit hyperactivity disorder in adolescents and adults protocol for a network meta analysis
url https://bmjopen.bmj.com/content/13/4/e068547.full
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