Target-specific peptides for BK virus agnoprotein identified through phage display screening: advancing antiviral therapeutics

Target-specific peptides for BK virus agnoprotein identified through phage display screening: advancing antiviral therapeutics

Abstract BK virus is implicated in polyomavirus-associated nephropathy (PVAN) and hemorrhagic cystitis, particularly in kidney transplant recipients, affecting the functionality of the transplanted kidney and posing a risk of graft loss. Despite these challenges, specific antiviral drugs targeting B...

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Bibliographic Details
Main Authors: Xiaofei Xing, Jingxian Han, Keke Wang, Fuyun Tian, CuiXia Jiang, Wei Liang, Lin Qi, Xin Yue, Yinhang Wen, Yuwei Hu, Hui Qiao
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
BK virus
Kidney transplant
Agnoprotein
Phage display technology
Peptide drugs
Online Access:https://doi.org/10.1038/s41598-025-86439-4
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