Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study

Background: Iodine is crucial for thyroid hormones, normal metabolism, growth and development in the foetal period. Low iodine status in women of childbearing age is particularly worrying since iodine deficiency continues into pregnancy. Objective: This study aimed to measure iodine status in non-pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Maren Johnsen, Guri Skeie, Tonje Braaten, Marianne Hope Abel, Sandra Huber, Marian Kjellevold, Elin Evensen, Margaret Rayman, Solrunn Hansen
Format: Article
Language:English
Published: Swedish Nutrition Foundation 2025-02-01
Series:Food & Nutrition Research
Subjects:
Online Access:https://foodandnutritionresearch.net/index.php/fnr/article/view/10802/19143
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850196400003874816
author Maren Johnsen
Guri Skeie
Tonje Braaten
Marianne Hope Abel
Sandra Huber
Marian Kjellevold
Elin Evensen
Margaret Rayman
Solrunn Hansen
author_facet Maren Johnsen
Guri Skeie
Tonje Braaten
Marianne Hope Abel
Sandra Huber
Marian Kjellevold
Elin Evensen
Margaret Rayman
Solrunn Hansen
author_sort Maren Johnsen
collection DOAJ
description Background: Iodine is crucial for thyroid hormones, normal metabolism, growth and development in the foetal period. Low iodine status in women of childbearing age is particularly worrying since iodine deficiency continues into pregnancy. Objective: This study aimed to measure iodine status in non-pregnant and pregnant women in Northern Norway and investigate group differences and determinants of urine iodine concentrations (UICs) based on dietary factors and participants’ knowledge about iodine. Methods: This cross-sectional study included pregnant (n = 131) and non-pregnant (n = 493) women from the Northern Norway Mother-and-Child Contaminant Cohort Study 2 study (2017–2021) and the Fit Futures 3 study (2020–2021). UIC was measured in spot urine, and dietary iodine intake was calculated from food frequency questionnaires. Group differences in median UIC were explored using non-parametric tests. Associations between independent variables and median UIC were estimated through quantile regression, adjusting for relevant covariates. Results: Median UIC was 91 μg/L in non-pregnant and 134 μg/L in pregnant women, thus below the World Health Organization definition of insufficient iodine status of < 100 μg/L and 150 μg/L, respectively. Dairy products and lean fish were the most important dietary iodine sources, but the median estimated intake did not reach the recommended intake. Taking iodine supplements was the strongest determinant of UIC in both groups (P < 0.01), and users had adequate iodine status at a group level. A high proportion of the non-pregnant women (84%) were not taking iodine supplements. Poor knowledge about iodine in the participant groups was observed but was not associated with UIC. Conclusion: Pregnant and non-pregnant women not using iodine supplements had inadequate iodine status and insufficient iodine intake. Supplement use or interventions at the societal level are essential to ensure adequate status in these vulnerable groups.
format Article
id doaj-art-e70dcf717e574e758b981ae93ee8c3fa
institution OA Journals
issn 1654-661X
language English
publishDate 2025-02-01
publisher Swedish Nutrition Foundation
record_format Article
series Food & Nutrition Research
spelling doaj-art-e70dcf717e574e758b981ae93ee8c3fa2025-08-20T02:13:28ZengSwedish Nutrition FoundationFood & Nutrition Research1654-661X2025-02-016911210.29219/fnr.v69.1080210802Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional studyMaren Johnsen0Guri Skeie1Tonje Braaten2Marianne Hope Abel3Sandra Huber4Marian Kjellevold5Elin Evensen6Margaret Rayman7Solrunn Hansen81Department of Health and Care Sciences, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway2Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway2Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway3Department of Physical Health and Ageing, Norwegian Institute of Public Health, Oslo, Norway4Department of Laboratory Medicine, University Hospital of North Norway, Tromsø, Norway5Institute of Marine Research (IMR), Bergen, Norway1Department of Health and Care Sciences, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway6Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom1Department of Health and Care Sciences, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, NorwayBackground: Iodine is crucial for thyroid hormones, normal metabolism, growth and development in the foetal period. Low iodine status in women of childbearing age is particularly worrying since iodine deficiency continues into pregnancy. Objective: This study aimed to measure iodine status in non-pregnant and pregnant women in Northern Norway and investigate group differences and determinants of urine iodine concentrations (UICs) based on dietary factors and participants’ knowledge about iodine. Methods: This cross-sectional study included pregnant (n = 131) and non-pregnant (n = 493) women from the Northern Norway Mother-and-Child Contaminant Cohort Study 2 study (2017–2021) and the Fit Futures 3 study (2020–2021). UIC was measured in spot urine, and dietary iodine intake was calculated from food frequency questionnaires. Group differences in median UIC were explored using non-parametric tests. Associations between independent variables and median UIC were estimated through quantile regression, adjusting for relevant covariates. Results: Median UIC was 91 μg/L in non-pregnant and 134 μg/L in pregnant women, thus below the World Health Organization definition of insufficient iodine status of < 100 μg/L and 150 μg/L, respectively. Dairy products and lean fish were the most important dietary iodine sources, but the median estimated intake did not reach the recommended intake. Taking iodine supplements was the strongest determinant of UIC in both groups (P < 0.01), and users had adequate iodine status at a group level. A high proportion of the non-pregnant women (84%) were not taking iodine supplements. Poor knowledge about iodine in the participant groups was observed but was not associated with UIC. Conclusion: Pregnant and non-pregnant women not using iodine supplements had inadequate iodine status and insufficient iodine intake. Supplement use or interventions at the societal level are essential to ensure adequate status in these vulnerable groups.https://foodandnutritionresearch.net/index.php/fnr/article/view/10802/19143iodine statusiodine intakepregnancywomennutrition
spellingShingle Maren Johnsen
Guri Skeie
Tonje Braaten
Marianne Hope Abel
Sandra Huber
Marian Kjellevold
Elin Evensen
Margaret Rayman
Solrunn Hansen
Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study
Food & Nutrition Research
iodine status
iodine intake
pregnancy
women
nutrition
title Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study
title_full Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study
title_fullStr Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study
title_full_unstemmed Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study
title_short Inadequate iodine status among women of childbearing age in Northern Norway: a cross-sectional study
title_sort inadequate iodine status among women of childbearing age in northern norway a cross sectional study
topic iodine status
iodine intake
pregnancy
women
nutrition
url https://foodandnutritionresearch.net/index.php/fnr/article/view/10802/19143
work_keys_str_mv AT marenjohnsen inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT guriskeie inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT tonjebraaten inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT mariannehopeabel inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT sandrahuber inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT mariankjellevold inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT elinevensen inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT margaretrayman inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy
AT solrunnhansen inadequateiodinestatusamongwomenofchildbearingageinnorthernnorwayacrosssectionalstudy