Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrier
The symbiotic relationship between the intestinal microbiota and its host is crucial to the development and functioning of both partners. The microbiota plays a key role in the development and physiology of its host (nutrition, growth, health and cognition). In turn, the host shapes the microbiota,...
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| Format: | Article |
| Language: | English |
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Universitat Politècnica de València
2025-06-01
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| Series: | World Rabbit Science |
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| Online Access: | https://polipapers.upv.es/index.php/wrs/article/view/23465 |
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| author | Sylvie Combes Laurent Cauquil Mathilde Rumeau Charlotte Paës Géraldine Pascal Cláudia M. Vicente Martin Beaumont Christelle Knudsen |
| author_facet | Sylvie Combes Laurent Cauquil Mathilde Rumeau Charlotte Paës Géraldine Pascal Cláudia M. Vicente Martin Beaumont Christelle Knudsen |
| author_sort | Sylvie Combes |
| collection | DOAJ |
| description | The symbiotic relationship between the intestinal microbiota and its host is crucial to the development and functioning of both partners. The microbiota plays a key role in the development and physiology of its host (nutrition, growth, health and cognition). In turn, the host shapes the microbiota, according to factors that are intrinsic or dependent on its environment. However, the definition of an optimal microbiota that maximises ecosystem services (host benefits) has yet not been established. The symbiotic relationship between the microbiota and its host is based on a complex molecular dialogue at the level of the intestinal epithelium and the underlying mucosal immune system. These interactions condition the establishment of an intestinal barrier, limiting colonisation by microbial pathogens and thereby guaranteeing health. In this review, we propose a ‘core’ rabbit microbiota definition through a re-analysis of available opensource data. Based on the association between the abundance of bacterial taxa and host traits, we attempt to identify microbiota key species that would likely be involved in growth performance and health. Then, we describe the components of the intestinal barrier and the host-microbiota interaction mechanisms. Finally, we propose early in life nutritional levers to strengthen this intestinal barrier and thereby enhance the health of young rabbits before weaning. |
| format | Article |
| id | doaj-art-e70c641e4f714313adcc150269de40c3 |
| institution | OA Journals |
| issn | 1257-5011 1989-8886 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Universitat Politècnica de València |
| record_format | Article |
| series | World Rabbit Science |
| spelling | doaj-art-e70c641e4f714313adcc150269de40c32025-08-20T02:38:15ZengUniversitat Politècnica de ValènciaWorld Rabbit Science1257-50111989-88862025-06-0133210312510.4995/wrs.2025.2346522655Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrierSylvie Combes0https://orcid.org/0000-0002-2945-4423Laurent Cauquil1https://orcid.org/0000-0002-0384-8811Mathilde Rumeau2https://orcid.org/0009-0004-8903-0966Charlotte Paës3https://orcid.org/0009-0002-4099-513XGéraldine Pascal4https://orcid.org/0000-0002-5250-6594Cláudia M. Vicente5https://orcid.org/0000-0001-8205-6486Martin Beaumont6https://orcid.org/0000-0002-1559-2067Christelle Knudsen7https://orcid.org/0000-0002-9587-8179Génétique Physiologie et Systèmes d'Elevage Génétique Physiologie et Systèmes d'Elevage Génétique Physiologie et Systèmes d'Elevage Génétique Physiologie et Systèmes d'Elevage Génétique Physiologie et Systèmes d'Elevage Génétique Physiologie et Systèmes d'Elevage Génétique Physiologie et Systèmes d'Elevage Génétique Physiologie et Systèmes d'Elevage The symbiotic relationship between the intestinal microbiota and its host is crucial to the development and functioning of both partners. The microbiota plays a key role in the development and physiology of its host (nutrition, growth, health and cognition). In turn, the host shapes the microbiota, according to factors that are intrinsic or dependent on its environment. However, the definition of an optimal microbiota that maximises ecosystem services (host benefits) has yet not been established. The symbiotic relationship between the microbiota and its host is based on a complex molecular dialogue at the level of the intestinal epithelium and the underlying mucosal immune system. These interactions condition the establishment of an intestinal barrier, limiting colonisation by microbial pathogens and thereby guaranteeing health. In this review, we propose a ‘core’ rabbit microbiota definition through a re-analysis of available opensource data. Based on the association between the abundance of bacterial taxa and host traits, we attempt to identify microbiota key species that would likely be involved in growth performance and health. Then, we describe the components of the intestinal barrier and the host-microbiota interaction mechanisms. Finally, we propose early in life nutritional levers to strengthen this intestinal barrier and thereby enhance the health of young rabbits before weaning.https://polipapers.upv.es/index.php/wrs/article/view/23465intestinal epitheliumimmune systemfeed transitionmeta-analysis |
| spellingShingle | Sylvie Combes Laurent Cauquil Mathilde Rumeau Charlotte Paës Géraldine Pascal Cláudia M. Vicente Martin Beaumont Christelle Knudsen Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrier World Rabbit Science intestinal epithelium immune system feed transition meta-analysis |
| title | Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrier |
| title_full | Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrier |
| title_fullStr | Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrier |
| title_full_unstemmed | Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrier |
| title_short | Core gut microbiota in rabbit: opportunities to strengthen the intestinal barrier |
| title_sort | core gut microbiota in rabbit opportunities to strengthen the intestinal barrier |
| topic | intestinal epithelium immune system feed transition meta-analysis |
| url | https://polipapers.upv.es/index.php/wrs/article/view/23465 |
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