Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021

ObjectivesTo analyze global trends in smoking-related disease burden from 1990–2021 and examine associations with health workforce distribution across countries.MethodsWe analyzed smoking-related deaths and disability-adjusted life years using Global Burden of Disease 2021 data for 204 countries. Ag...

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Main Authors: Yuzhou Cai, Guiming Chen, Peng Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:International Journal of Public Health
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Online Access:https://www.ssph-journal.org/articles/10.3389/ijph.2025.1608217/full
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author Yuzhou Cai
Guiming Chen
Peng Bai
author_facet Yuzhou Cai
Guiming Chen
Peng Bai
author_sort Yuzhou Cai
collection DOAJ
description ObjectivesTo analyze global trends in smoking-related disease burden from 1990–2021 and examine associations with health workforce distribution across countries.MethodsWe analyzed smoking-related deaths and disability-adjusted life years using Global Burden of Disease 2021 data for 204 countries. Age-standardized rates were calculated for 27 geographic regions. Linear regression assessed temporal trends, while autoregressive integrated moving average models projected future burden to 2050. Correlation analyses examined relationships between 22 health workforce categories and disease burden.ResultsGlobally, age-standardized death rates from smoking-related diseases increased by 12.3% from 1990–2021, with males showing higher rates than females across all regions. Middle Socio-demographic Index regions exhibited the highest burden. Pharmaceutical technicians demonstrated strong positive correlations with disease burden (r = 0.35–0.37, p < 0.001), while traditional practitioners showed negative correlations (r = −0.24 to −0.28, p < 0.001). Projections indicate continued increases through 2050.ConclusionSmoking-related disease burden demonstrates significant geographic and temporal variations, with distinct associations between health workforce composition and disease patterns, highlighting the need for targeted prevention strategies.
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spelling doaj-art-e70be9cc99e541549c3737f6d864d1e82025-08-20T03:39:21ZengFrontiers Media S.A.International Journal of Public Health1661-85642025-07-017010.3389/ijph.2025.16082171608217Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021Yuzhou Cai0Guiming Chen1Peng Bai2Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, ChinaInterventional Medicine Department, The First Affiliated Hospital of Kunming Medical University, Kunming, ChinaInterventional Medicine Department, The First Affiliated Hospital of Kunming Medical University, Kunming, ChinaObjectivesTo analyze global trends in smoking-related disease burden from 1990–2021 and examine associations with health workforce distribution across countries.MethodsWe analyzed smoking-related deaths and disability-adjusted life years using Global Burden of Disease 2021 data for 204 countries. Age-standardized rates were calculated for 27 geographic regions. Linear regression assessed temporal trends, while autoregressive integrated moving average models projected future burden to 2050. Correlation analyses examined relationships between 22 health workforce categories and disease burden.ResultsGlobally, age-standardized death rates from smoking-related diseases increased by 12.3% from 1990–2021, with males showing higher rates than females across all regions. Middle Socio-demographic Index regions exhibited the highest burden. Pharmaceutical technicians demonstrated strong positive correlations with disease burden (r = 0.35–0.37, p < 0.001), while traditional practitioners showed negative correlations (r = −0.24 to −0.28, p < 0.001). Projections indicate continued increases through 2050.ConclusionSmoking-related disease burden demonstrates significant geographic and temporal variations, with distinct associations between health workforce composition and disease patterns, highlighting the need for targeted prevention strategies.https://www.ssph-journal.org/articles/10.3389/ijph.2025.1608217/fullsmoking-related diseasesglobal health burdenhealth workforcedisease trendsprevention strategies
spellingShingle Yuzhou Cai
Guiming Chen
Peng Bai
Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021
International Journal of Public Health
smoking-related diseases
global health burden
health workforce
disease trends
prevention strategies
title Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021
title_full Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021
title_fullStr Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021
title_full_unstemmed Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021
title_short Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2021
title_sort global regional and national burden of smoking related diseases and associations with health workforce distribution 1990 2021 analysis from the global burden of disease study 2021
topic smoking-related diseases
global health burden
health workforce
disease trends
prevention strategies
url https://www.ssph-journal.org/articles/10.3389/ijph.2025.1608217/full
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