The role of GABA in type 1 diabetes

The role of GABA in type 1 diabetes

Gamma aminobutyric acid (GABA) is synthesized from glutamate by glutamic decarboxylase (GAD). The entero-pancreatic biology of GABA, which is produced by pancreatic islets, GAD-expressing microbiota, enteric immune cells, or ingested through diet, supports an essential physiologic role of GABA in th...

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Bibliographic Details
Main Authors:	Gail J. Mick, Kenneth L. McCormick
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Series:	Frontiers in Endocrinology
Subjects:	gamma aminobutyric acid (GABA) Type 1 diabetes GABA treatment/diabetes β-cells/pancreatic islets α-cells/glucagon diabetes/new therapies
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1453396/full
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