THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMA
The features of expression of translocator protein (TSPO) and cytochrome P450scc (CYP 450scc) in patients with renal cell carcinoma (RCC) were described in the article. The dependence of level expression of TSPO from stage and histological subtypes of renal cell carcinoma were established. The chang...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/130 |
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| author | R. A. Zukov T. G. Ruksha Yu. A. Dykhno E. V. Semenov N. V. Boyakova |
| author_facet | R. A. Zukov T. G. Ruksha Yu. A. Dykhno E. V. Semenov N. V. Boyakova |
| author_sort | R. A. Zukov |
| collection | DOAJ |
| description | The features of expression of translocator protein (TSPO) and cytochrome P450scc (CYP 450scc) in patients with renal cell carcinoma (RCC) were described in the article. The dependence of level expression of TSPO from stage and histological subtypes of renal cell carcinoma were established. The changing of expression level of CYP 450scc in tumor cells indicates a change of severity of steroidogenesis in different histological subtypes of RCC. These findings were important for interpretation the pathogenesis of RCC and also they could have prognostic value |
| format | Article |
| id | doaj-art-e6f28081d91c43e39843786bee37af65 |
| institution | Kabale University |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2016-02-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-e6f28081d91c43e39843786bee37af652025-08-20T03:35:50ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-01034751130THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMAR. A. Zukov0T. G. Ruksha1Yu. A. Dykhno2E. V. Semenov3N. V. Boyakova4V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityThe features of expression of translocator protein (TSPO) and cytochrome P450scc (CYP 450scc) in patients with renal cell carcinoma (RCC) were described in the article. The dependence of level expression of TSPO from stage and histological subtypes of renal cell carcinoma were established. The changing of expression level of CYP 450scc in tumor cells indicates a change of severity of steroidogenesis in different histological subtypes of RCC. These findings were important for interpretation the pathogenesis of RCC and also they could have prognostic valuehttps://www.siboncoj.ru/jour/article/view/130renal cell carcinomatspocytochrome p450sccsteroidogenesis |
| spellingShingle | R. A. Zukov T. G. Ruksha Yu. A. Dykhno E. V. Semenov N. V. Boyakova THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMA Сибирский онкологический журнал renal cell carcinoma tspo cytochrome p450scc steroidogenesis |
| title | THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMA |
| title_full | THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMA |
| title_fullStr | THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMA |
| title_full_unstemmed | THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMA |
| title_short | THE DEPENDENCE OF TRANSLOCATOR PROTEIN TSPO LEVEL AND CYTOCHROME P450SCC FROM HISTOTYPE OF TUMOR IN PATIENTS WITH RENAL CELL CARCINOMA |
| title_sort | dependence of translocator protein tspo level and cytochrome p450scc from histotype of tumor in patients with renal cell carcinoma |
| topic | renal cell carcinoma tspo cytochrome p450scc steroidogenesis |
| url | https://www.siboncoj.ru/jour/article/view/130 |
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