A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid

We report a case of disseminated herpes zoster diagnosed by high-throughput sequencing. A 74-year-old female presented with a one-week history of abdominal pain and distension. Two months ago, she was diagnosed with ANCA-associated vasculitis and received immunosuppressive therapy. One week ago, she...

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Main Authors: GUI Yu, CHEN Jiajie, YU Shuling, LIU Siqi, LIU Shengxiu
Format: Article
Language:zho
Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2025-05-01
Series:Pifu-xingbing zhenliaoxue zazhi
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Online Access:http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.05.008
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author GUI Yu
CHEN Jiajie
YU Shuling
LIU Siqi
LIU Shengxiu
author_facet GUI Yu
CHEN Jiajie
YU Shuling
LIU Siqi
LIU Shengxiu
author_sort GUI Yu
collection DOAJ
description We report a case of disseminated herpes zoster diagnosed by high-throughput sequencing. A 74-year-old female presented with a one-week history of abdominal pain and distension. Two months ago, she was diagnosed with ANCA-associated vasculitis and received immunosuppressive therapy. One week ago, she developed unexplained abdominal pain. Pathogen DNA sequencing of ascitic fluid indicated varicella-zoster virus infection. Two days later, the patient developed clustered hemorrhagic blisters with pain on her left lower limb. The patient was diagnosed with disseminated herpes zoster. Despite active treatment, the therapeutic response was unsatisfactory. The patient did not pursue further treatment and is currently lost to follow-up.
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issn 1674-8468
language zho
publishDate 2025-05-01
publisher editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
record_format Article
series Pifu-xingbing zhenliaoxue zazhi
spelling doaj-art-e6e96abb1d7c4429952239141817e84b2025-08-20T03:15:54Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682025-05-0132535535810.3969/j.issn.1674-8468.2025.05.008A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluidGUI Yu0CHEN Jiajie1YU Shuling2LIU Siqi3LIU Shengxiu4First Affiliated Hospital of Anhui Medical University, Hefei 230022, ChinaFirst Affiliated Hospital of Anhui Medical University, Hefei 230022, ChinaFirst Affiliated Hospital of Anhui Medical University, Hefei 230022, ChinaFirst Affiliated Hospital of Anhui Medical University, Hefei 230022, ChinaFirst Affiliated Hospital of Anhui Medical University, Hefei 230022, ChinaWe report a case of disseminated herpes zoster diagnosed by high-throughput sequencing. A 74-year-old female presented with a one-week history of abdominal pain and distension. Two months ago, she was diagnosed with ANCA-associated vasculitis and received immunosuppressive therapy. One week ago, she developed unexplained abdominal pain. Pathogen DNA sequencing of ascitic fluid indicated varicella-zoster virus infection. Two days later, the patient developed clustered hemorrhagic blisters with pain on her left lower limb. The patient was diagnosed with disseminated herpes zoster. Despite active treatment, the therapeutic response was unsatisfactory. The patient did not pursue further treatment and is currently lost to follow-up.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.05.008disseminated herpes zosterstomachachehigh-throughput sequencing
spellingShingle GUI Yu
CHEN Jiajie
YU Shuling
LIU Siqi
LIU Shengxiu
A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
Pifu-xingbing zhenliaoxue zazhi
disseminated herpes zoster
stomachache
high-throughput sequencing
title A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
title_full A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
title_fullStr A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
title_full_unstemmed A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
title_short A case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
title_sort case of disseminated herpes zoster diagnosed by metagenomic analysis of ascitic fluid
topic disseminated herpes zoster
stomachache
high-throughput sequencing
url http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.05.008
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