Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern India
Background. Acute respiratory infections (ARIs) are important cause of mortality and morbidity in children under five in developing country. Methods. This observational study was conducted over two-year period in a tertiary care teaching hospital of Eastern India. Nasal and throat swabs were collect...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2016/7235482 |
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| author | Pravakar Mishra Lipika Nayak Rashmi Ranjan Das Bhagirathi Dwibedi Amitabh Singh |
| author_facet | Pravakar Mishra Lipika Nayak Rashmi Ranjan Das Bhagirathi Dwibedi Amitabh Singh |
| author_sort | Pravakar Mishra |
| collection | DOAJ |
| description | Background. Acute respiratory infections (ARIs) are important cause of mortality and morbidity in children under five in developing country. Methods. This observational study was conducted over two-year period in a tertiary care teaching hospital of Eastern India. Nasal and throat swabs were collected, transported to the laboratory at 2–8°C in viral transport media, and then processed for detection of viruses using mono/multiplex real-time polymerase chain reaction. Results. A total of 300 children aged 2–60 months with ARIs were included. The most common age group affected with LRI was 2–12 mo and with URI was >12–60 mo. Viruses were detected in 248 cases. In URI, 77 were positive for single virus and 19 were positive for more than one virus; in LRI, 113 were positive for single virus and 12 were positive for more than one virus. The most common viruses isolated from URI cases were rhinovirus and adenovirus. The most common viruses isolated from LRI cases were respiratory syncytial virus and influenza virus. Most cases occurred in the months of January, December, and August. Conclusion. Viruses constitute a significant cause of ARI in children under five. RSV, ADV, RV, and IFV were the most prevalent viruses isolated. |
| format | Article |
| id | doaj-art-e6e3b81a5b4942ae86e8e717957d75c1 |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-e6e3b81a5b4942ae86e8e717957d75c12025-08-20T03:26:11ZengWileyInternational Journal of Pediatrics1687-97401687-97592016-01-01201610.1155/2016/72354827235482Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern IndiaPravakar Mishra0Lipika Nayak1Rashmi Ranjan Das2Bhagirathi Dwibedi3Amitabh Singh4SVP Post Graduate Institute of Paediatrics, SCB Medical College & Hospital, Cuttack 753007, IndiaSVP Post Graduate Institute of Paediatrics, SCB Medical College & Hospital, Cuttack 753007, IndiaDepartment of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar 751019, IndiaRegional Medical Research Centre (ICMR), Bhubaneswar 751016, IndiaDepartment of Pediatrics, Chacha Nehru Bal Chikitsalaya, New Delhi 110031, IndiaBackground. Acute respiratory infections (ARIs) are important cause of mortality and morbidity in children under five in developing country. Methods. This observational study was conducted over two-year period in a tertiary care teaching hospital of Eastern India. Nasal and throat swabs were collected, transported to the laboratory at 2–8°C in viral transport media, and then processed for detection of viruses using mono/multiplex real-time polymerase chain reaction. Results. A total of 300 children aged 2–60 months with ARIs were included. The most common age group affected with LRI was 2–12 mo and with URI was >12–60 mo. Viruses were detected in 248 cases. In URI, 77 were positive for single virus and 19 were positive for more than one virus; in LRI, 113 were positive for single virus and 12 were positive for more than one virus. The most common viruses isolated from URI cases were rhinovirus and adenovirus. The most common viruses isolated from LRI cases were respiratory syncytial virus and influenza virus. Most cases occurred in the months of January, December, and August. Conclusion. Viruses constitute a significant cause of ARI in children under five. RSV, ADV, RV, and IFV were the most prevalent viruses isolated.http://dx.doi.org/10.1155/2016/7235482 |
| spellingShingle | Pravakar Mishra Lipika Nayak Rashmi Ranjan Das Bhagirathi Dwibedi Amitabh Singh Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern India International Journal of Pediatrics |
| title | Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern India |
| title_full | Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern India |
| title_fullStr | Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern India |
| title_full_unstemmed | Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern India |
| title_short | Viral Agents Causing Acute Respiratory Infections in Children under Five: A Study from Eastern India |
| title_sort | viral agents causing acute respiratory infections in children under five a study from eastern india |
| url | http://dx.doi.org/10.1155/2016/7235482 |
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