Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus
An experiment was conducted to assess malathion-induced hematological responses of Barbonymus gonionotus (silver barb) and its recovery patterns in malathion-free water. Fish (45 days old) were exposed to two sublethal concentrations, namely, 25% and 50% (i.e., 3.78 and 7.56 ppm) of LC50 (15.13 ppm)...
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| Format: | Article |
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Wiley
2021-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2021/9417380 |
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| author | Cynthia E. Mrong Md. R. Islam Kamrunnaher Kole Nusrat N. Neepa Md. J. Alam Md. R. Haque Umme O. Rahman Golam M. Mostakim |
| author_facet | Cynthia E. Mrong Md. R. Islam Kamrunnaher Kole Nusrat N. Neepa Md. J. Alam Md. R. Haque Umme O. Rahman Golam M. Mostakim |
| author_sort | Cynthia E. Mrong |
| collection | DOAJ |
| description | An experiment was conducted to assess malathion-induced hematological responses of Barbonymus gonionotus (silver barb) and its recovery patterns in malathion-free water. Fish (45 days old) were exposed to two sublethal concentrations, namely, 25% and 50% (i.e., 3.78 and 7.56 ppm) of LC50 (15.13 ppm) of malathion for 28 days, followed by a postexposure recovery period for the same time. The hematological parameters were examined after 1, 7, 14, 21, and 28 days of exposure as well as after the postexposure recovery time. Except in the case of the control group (0% of malathion), the obtained results revealed that malathion exposure resulted in significantly (p<0.05) higher prevalence and severity of micronucleus and lower values of Hb, PCV, and RBC and significantly higher values of WBC in a concentration- and time-dependent manner. The values of blood glucose, MCV, MCH, and MCHC showed mixed trends during the experiment. During the recovery period, all blood parameters (micronucleus, glucose, Hb, PCV, RBC, WBC, MCV, MCH, and MCHC) partially recovered, which means that the recovery period was not long enough for the organisms to recover from the previous exposure. The study thus confirms that hematology is a sensitive indicator for fish to detect toxicity caused by different chemicals. Changes in these parameters can provide useful information about environmental conditions and risk assessment of aquatic organisms. |
| format | Article |
| id | doaj-art-e6e26ac2e2534008872cb550a53e265f |
| institution | Kabale University |
| issn | 1687-8205 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-e6e26ac2e2534008872cb550a53e265f2025-02-03T06:00:49ZengWileyJournal of Toxicology1687-82052021-01-01202110.1155/2021/9417380Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotusCynthia E. Mrong0Md. R. Islam1Kamrunnaher Kole2Nusrat N. Neepa3Md. J. Alam4Md. R. Haque5Umme O. Rahman6Golam M. Mostakim7Department of Fisheries Biology and Aquatic EnvironmentDepartment of AquacultureDepartment of Fisheries Biology and Aquatic EnvironmentDepartment of Fisheries Biology and Aquatic EnvironmentDepartment of Fisheries Biology and Aquatic EnvironmentDepartment of Biochemistry and Molecular BiologyDepartment of Fisheries Biology and GeneticsGraduate Training InstituteAn experiment was conducted to assess malathion-induced hematological responses of Barbonymus gonionotus (silver barb) and its recovery patterns in malathion-free water. Fish (45 days old) were exposed to two sublethal concentrations, namely, 25% and 50% (i.e., 3.78 and 7.56 ppm) of LC50 (15.13 ppm) of malathion for 28 days, followed by a postexposure recovery period for the same time. The hematological parameters were examined after 1, 7, 14, 21, and 28 days of exposure as well as after the postexposure recovery time. Except in the case of the control group (0% of malathion), the obtained results revealed that malathion exposure resulted in significantly (p<0.05) higher prevalence and severity of micronucleus and lower values of Hb, PCV, and RBC and significantly higher values of WBC in a concentration- and time-dependent manner. The values of blood glucose, MCV, MCH, and MCHC showed mixed trends during the experiment. During the recovery period, all blood parameters (micronucleus, glucose, Hb, PCV, RBC, WBC, MCV, MCH, and MCHC) partially recovered, which means that the recovery period was not long enough for the organisms to recover from the previous exposure. The study thus confirms that hematology is a sensitive indicator for fish to detect toxicity caused by different chemicals. Changes in these parameters can provide useful information about environmental conditions and risk assessment of aquatic organisms.http://dx.doi.org/10.1155/2021/9417380 |
| spellingShingle | Cynthia E. Mrong Md. R. Islam Kamrunnaher Kole Nusrat N. Neepa Md. J. Alam Md. R. Haque Umme O. Rahman Golam M. Mostakim Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus Journal of Toxicology |
| title | Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus |
| title_full | Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus |
| title_fullStr | Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus |
| title_full_unstemmed | Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus |
| title_short | Malathion-Induced Hematoxicity and Its Recovery Pattern in Barbonymus gonionotus |
| title_sort | malathion induced hematoxicity and its recovery pattern in barbonymus gonionotus |
| url | http://dx.doi.org/10.1155/2021/9417380 |
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