An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivatives

A rapid, highly efficient and mild green synthesis of benzoin was performed using substituted benzaldehyde catalyzed by KCN and imidazolium salts in EtOH/H2O under ultrasonic activation. The products were obtained in good yields within short reaction times with N,N′-dialkylimidazolium salts, which w...

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Main Authors: Javad Safari, Zohre Zarnegar, Masoume Ahmadi, Susan Seyyedi
Format: Article
Language:English
Published: Springer 2015-11-01
Series:Journal of Saudi Chemical Society
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Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312000610
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author Javad Safari
Zohre Zarnegar
Masoume Ahmadi
Susan Seyyedi
author_facet Javad Safari
Zohre Zarnegar
Masoume Ahmadi
Susan Seyyedi
author_sort Javad Safari
collection DOAJ
description A rapid, highly efficient and mild green synthesis of benzoin was performed using substituted benzaldehyde catalyzed by KCN and imidazolium salts in EtOH/H2O under ultrasonic activation. The products were obtained in good yields within short reaction times with N,N′-dialkylimidazolium salts, which were found to be more effective pre-catalysts at room temperature for benzoin condensation in comparison to corresponding cyanide ion in heating method. This simple method affords benzoin derivatives at room temperature in short reaction times with high yield and purity.
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spelling doaj-art-e6db5ad933b44c34a7654aeca84032ff2025-08-20T03:52:04ZengSpringerJournal of Saudi Chemical Society1319-61032015-11-0119662863310.1016/j.jscs.2012.05.005An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivativesJavad Safari0Zohre Zarnegar1Masoume Ahmadi2Susan Seyyedi3Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box 87317-51167, Kashan, I.R., IranLaboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box 87317-51167, Kashan, I.R., IranLaboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box 87317-51167, Kashan, I.R., IranFaculty of Science, DareShahr Branch, Islamic Azad University, Ilam, I.R., IranA rapid, highly efficient and mild green synthesis of benzoin was performed using substituted benzaldehyde catalyzed by KCN and imidazolium salts in EtOH/H2O under ultrasonic activation. The products were obtained in good yields within short reaction times with N,N′-dialkylimidazolium salts, which were found to be more effective pre-catalysts at room temperature for benzoin condensation in comparison to corresponding cyanide ion in heating method. This simple method affords benzoin derivatives at room temperature in short reaction times with high yield and purity.http://www.sciencedirect.com/science/article/pii/S1319610312000610Benzoin condensationCatalystsCyanide ionImidazolium saltsUltrasonic
spellingShingle Javad Safari
Zohre Zarnegar
Masoume Ahmadi
Susan Seyyedi
An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivatives
Journal of Saudi Chemical Society
Benzoin condensation
Catalysts
Cyanide ion
Imidazolium salts
Ultrasonic
title An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivatives
title_full An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivatives
title_fullStr An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivatives
title_full_unstemmed An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivatives
title_short An investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound-assisted synthesis of benzoin derivatives
title_sort investigation of the catalytic potential of potassium cyanide and imidazolium salts for ultrasound assisted synthesis of benzoin derivatives
topic Benzoin condensation
Catalysts
Cyanide ion
Imidazolium salts
Ultrasonic
url http://www.sciencedirect.com/science/article/pii/S1319610312000610
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