Exploring the impact of macrophage polarization and Modic changes on baseline clinical condition in radiculopathy due to lumbar disc herniation

Exploring the impact of macrophage polarization and Modic changes on baseline clinical condition in radiculopathy due to lumbar disc herniation

Introduction: Lumbar intervertebral disc herniation (LDH) often manifests as sciatica, resulting from mechanical compression and/or an inflammation affecting the nerve root. Research question: This study aims to investigate the impact of inflammation and macrophage polarization on clinical symptoms...

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Bibliographic Details
Main Authors: Wensen Li, Niek Djuric, Christiaan Mink, Carmen L.A. Vleggeert-Lankamp
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain and Spine
Subjects:
Sciatica
Lumbar
Inflammation
Macrophage
M1 and M2
Modic changes
Online Access:http://www.sciencedirect.com/science/article/pii/S2772529425002073
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