Parenteral administration medicines: recommendations of preparation, administration and stability

Objective: To develop recommendations for the preparation of parenteral drugs (MAP), to assess the transferability of their preparation, from nursing units in the hospital ward to the pharmacy service (SF). Method: A table of stabilities of parenteral drugs included in the pharmacotherapeutic guide...

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Main Authors: M. Gaspar Carreño, F. Torrico Martín, L. Novajarque Sala, M. Batista Cruz, P. Ribeiro Gonçalves, B. Porta Oltra, J. C. Sánchez Santos
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Farmacia Hospitalaria
Subjects:
Online Access:http://www.aulamedica.es/fh/pdf/7524.pdf
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author M. Gaspar Carreño
F. Torrico Martín
L. Novajarque Sala
M. Batista Cruz
P. Ribeiro Gonçalves
B. Porta Oltra
J. C. Sánchez Santos
author_facet M. Gaspar Carreño
F. Torrico Martín
L. Novajarque Sala
M. Batista Cruz
P. Ribeiro Gonçalves
B. Porta Oltra
J. C. Sánchez Santos
author_sort M. Gaspar Carreño
collection DOAJ
description Objective: To develop recommendations for the preparation of parenteral drugs (MAP), to assess the transferability of their preparation, from nursing units in the hospital ward to the pharmacy service (SF). Method: A table of stabilities of parenteral drugs included in the pharmacotherapeutic guideline was developed using the american and spanish guidelines. Information about MAP was collected (method of preparation, support, maintenance, validity, administration specifications and packaging) by consulting product technical sheets, pharmaceutical industries, literature review and databases. Results: After reviewing 209 drugs, a list of recommendations was developed. According to the data, MAP will be prepared as follows: 89 drugs will be prepared from SF, 62 drugs at nursing units because of its immediate administration requirement and 58 are already packed for its administration by the industry. Of these 62 drugs prepared a nursing units, 14 of them will be prepared in the following doses by the SF. Therefore, 48 drugs will be prepared at nursing units from the 209 parenteral drugs reviewed. Conclusions: A standardized method of preparation, storage, administration and validity of MAP was established by the SF. The preparation of MAP in the SF extends its shelf life, by considering physicochemical stability, level of risk and product vulnerability to microbiological contamination. The information provided will contribute to a reduction of errors associated with the preparation and administration of MAP.
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spelling doaj-art-e6d423fe42cd46129a4ae906b322defd2025-08-20T02:56:46ZengElsevierFarmacia Hospitalaria1130-63432171-86952014-11-0138646146710.7399/fh.2014.38.6.7524Parenteral administration medicines: recommendations of preparation, administration and stabilityM. Gaspar Carreño0F. Torrico Martín1L. Novajarque Sala2M. Batista Cruz3P. Ribeiro Gonçalves4B. Porta Oltra5J. C. Sánchez Santos6Servicio de Farmacia. Hospital Intermutual de Levante. Valencia.Servicio de Farmacia. Hospital Intermutual de Levante. ValenciaServicio de Farmacia. Hospital Intermutual de Levante. ValenciaDepartamento de Farmacia. CEU Universidad Cardenal Herrera. Valencia. Faculdade de Farmácia da Universidade do Porto. Porto. PortugalDepartamento de Farmacia. CEU Universidad Cardenal Herrera. Valencia. Faculdade de Farmácia da Universidade do Porto. Porto. Portugal.Hospital Universitario Dr. Peset. Valencia.Hospital Universitario Dr. Peset. Valencia.Objective: To develop recommendations for the preparation of parenteral drugs (MAP), to assess the transferability of their preparation, from nursing units in the hospital ward to the pharmacy service (SF). Method: A table of stabilities of parenteral drugs included in the pharmacotherapeutic guideline was developed using the american and spanish guidelines. Information about MAP was collected (method of preparation, support, maintenance, validity, administration specifications and packaging) by consulting product technical sheets, pharmaceutical industries, literature review and databases. Results: After reviewing 209 drugs, a list of recommendations was developed. According to the data, MAP will be prepared as follows: 89 drugs will be prepared from SF, 62 drugs at nursing units because of its immediate administration requirement and 58 are already packed for its administration by the industry. Of these 62 drugs prepared a nursing units, 14 of them will be prepared in the following doses by the SF. Therefore, 48 drugs will be prepared at nursing units from the 209 parenteral drugs reviewed. Conclusions: A standardized method of preparation, storage, administration and validity of MAP was established by the SF. The preparation of MAP in the SF extends its shelf life, by considering physicochemical stability, level of risk and product vulnerability to microbiological contamination. The information provided will contribute to a reduction of errors associated with the preparation and administration of MAP.http://www.aulamedica.es/fh/pdf/7524.pdfInfusion drugs; Drug stability; DrugPharmacy service; Nursing units
spellingShingle M. Gaspar Carreño
F. Torrico Martín
L. Novajarque Sala
M. Batista Cruz
P. Ribeiro Gonçalves
B. Porta Oltra
J. C. Sánchez Santos
Parenteral administration medicines: recommendations of preparation, administration and stability
Farmacia Hospitalaria
Infusion drugs
; Drug stability
; Drug
Pharmacy service
; Nursing units
title Parenteral administration medicines: recommendations of preparation, administration and stability
title_full Parenteral administration medicines: recommendations of preparation, administration and stability
title_fullStr Parenteral administration medicines: recommendations of preparation, administration and stability
title_full_unstemmed Parenteral administration medicines: recommendations of preparation, administration and stability
title_short Parenteral administration medicines: recommendations of preparation, administration and stability
title_sort parenteral administration medicines recommendations of preparation administration and stability
topic Infusion drugs
; Drug stability
; Drug
Pharmacy service
; Nursing units
url http://www.aulamedica.es/fh/pdf/7524.pdf
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