Genistein Improves the Cytotoxic, Apoptotic, and Oxidative-Stress-Inducing Properties of Doxorubicin in SK-MEL-28 Cancer Cells

Genistein Improves the Cytotoxic, Apoptotic, and Oxidative-Stress-Inducing Properties of Doxorubicin in SK-MEL-28 Cancer Cells

<i>Background and Objectives:</i> Cutaneous melanoma (CM) poses a continuous challenge in oncology due to the developing resistance to available treatments. Doxorubicin (DOX) is noted as one of the most effective chemotherapeutics, although associated toxicity and resistance limit its us...

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Bibliographic Details
Main Authors: Andrea Roman, Andrei Motoc, Iasmina Marcovici, Cristina Dehelean, Laura Nicolescu, Casiana Boru
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Medicina
Subjects:
cutaneous melanoma cells
genistein
doxorubicin
cytotoxicity
apoptosis
oxidative stress
Online Access:https://www.mdpi.com/1648-9144/61/5/798
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