Impact of Recovery from Febrile Neutropenia on Intra-Individual Variability in Vancomycin Pharmacokinetics in Pediatric Patients

Impact of Recovery from Febrile Neutropenia on Intra-Individual Variability in Vancomycin Pharmacokinetics in Pediatric Patients

Background/Objectives: The pharmacokinetics of vancomycin (VCM) in patients with febrile neutropenia (FN) are highly variable due to coexisting conditions such as systemic inflammatory response syndrome and augmented renal clearance. Upon hematopoietic recovery, VCM clearance (CLvcm) is expected to...

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Bibliographic Details
Main Authors: Yukie Takumi, Ryota Tanaka, Motoshi Iwao, Ryosuke Tatsuta, Hiroki Itoh
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Antibiotics
Subjects:
febrile neutropenia
vancomycin
intra-individual
therapeutic drug monitoring
Online Access:https://www.mdpi.com/2079-6382/14/6/570
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