Water and electrolyte imbalance in patients with metabolic syndrome

Considering the high incidence of renal impairment in metabolic syndrome (MS), an analysis of electrolyte metabolism was performed in 112 patients preoperatively and 53 patients postoperatively. Aldosterone level, adrenocorticotropic hormone level, neutrophil gelatinase-associated lipocalin level, c...

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Main Authors: V. N. Pavlov, A. V. Alekseyev, R. R. Ishemgulov, A. A. Ismailov, Zh. A. Galeyeva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2012-04-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/448
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author V. N. Pavlov
A. V. Alekseyev
R. R. Ishemgulov
A. A. Ismailov
Zh. A. Galeyeva
author_facet V. N. Pavlov
A. V. Alekseyev
R. R. Ishemgulov
A. A. Ismailov
Zh. A. Galeyeva
author_sort V. N. Pavlov
collection DOAJ
description Considering the high incidence of renal impairment in metabolic syndrome (MS), an analysis of electrolyte metabolism was performed in 112 patients preoperatively and 53 patients postoperatively. Aldosterone level, adrenocorticotropic hormone level, neutrophil gelatinase-associated lipocalin level, cortisol level, β2-microglobulin level, serum vasopressin level, urinary microalbumin level measurements were taken as a combined patient assessment procedure. MS patients were found to demonstrate a decrease in circadian amounts of urea, potassium, sodium and chlorides excretion. An increase in vasopressin production and an enhancement of microalbumin excretion were detected. The specified disturbances developed as «a vicious circle»: fluid retention resulted in heperfiltration, with renal dysfunction leading to a deteriorated hydro-electrolyte imbalance. An improvement of circadian electrolyte excretion rates, as well as a decline in vasopressin and cortisol levels, occurred due to a reduction of abdominal fat volume.
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issn 1682-0363
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language English
publishDate 2012-04-01
publisher Siberian State Medical University (Tomsk)
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series Бюллетень сибирской медицины
spelling doaj-art-e6c1b36acbe54931aedd3b50a1e8725b2025-08-20T03:02:22ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-04-01112404310.20538/1682-0363-2012-2-40-43423Water and electrolyte imbalance in patients with metabolic syndromeV. N. Pavlov0A. V. Alekseyev1R. R. Ishemgulov2A. A. Ismailov3Zh. A. Galeyeva4Башкирский государственный медицинский университет, г. УфаГБУЗ «Республиканская клиническая больница им. Г.Г. Куватова», г. УфаБашкирский государственный медицинский университет, г. УфаБашкирский государственный медицинский университет, г. УфаБашкирский государственный медицинский университет, г. УфаConsidering the high incidence of renal impairment in metabolic syndrome (MS), an analysis of electrolyte metabolism was performed in 112 patients preoperatively and 53 patients postoperatively. Aldosterone level, adrenocorticotropic hormone level, neutrophil gelatinase-associated lipocalin level, cortisol level, β2-microglobulin level, serum vasopressin level, urinary microalbumin level measurements were taken as a combined patient assessment procedure. MS patients were found to demonstrate a decrease in circadian amounts of urea, potassium, sodium and chlorides excretion. An increase in vasopressin production and an enhancement of microalbumin excretion were detected. The specified disturbances developed as «a vicious circle»: fluid retention resulted in heperfiltration, with renal dysfunction leading to a deteriorated hydro-electrolyte imbalance. An improvement of circadian electrolyte excretion rates, as well as a decline in vasopressin and cortisol levels, occurred due to a reduction of abdominal fat volume.https://bulletin.ssmu.ru/jour/article/view/448metabolic syndromehydro-electrolyte metabolismvasopressincortisol (hydrocortisone)
spellingShingle V. N. Pavlov
A. V. Alekseyev
R. R. Ishemgulov
A. A. Ismailov
Zh. A. Galeyeva
Water and electrolyte imbalance in patients with metabolic syndrome
Бюллетень сибирской медицины
metabolic syndrome
hydro-electrolyte metabolism
vasopressin
cortisol (hydrocortisone)
title Water and electrolyte imbalance in patients with metabolic syndrome
title_full Water and electrolyte imbalance in patients with metabolic syndrome
title_fullStr Water and electrolyte imbalance in patients with metabolic syndrome
title_full_unstemmed Water and electrolyte imbalance in patients with metabolic syndrome
title_short Water and electrolyte imbalance in patients with metabolic syndrome
title_sort water and electrolyte imbalance in patients with metabolic syndrome
topic metabolic syndrome
hydro-electrolyte metabolism
vasopressin
cortisol (hydrocortisone)
url https://bulletin.ssmu.ru/jour/article/view/448
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AT rrishemgulov waterandelectrolyteimbalanceinpatientswithmetabolicsyndrome
AT aaismailov waterandelectrolyteimbalanceinpatientswithmetabolicsyndrome
AT zhagaleyeva waterandelectrolyteimbalanceinpatientswithmetabolicsyndrome