Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes
BCP are considered the most promising biomaterials for bone reconstruction. This study aims at analyzing the outcomes of patients who received BCP as bone substitutes in orthopaedic surgeries. Sixty-six patients were categorized according to the etiology and morphology of the bone defects and receiv...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Biomaterials |
| Online Access: | http://dx.doi.org/10.1155/2011/129727 |
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| author | Carlos A. Garrido Sonja E. Lobo Flávio M. Turíbio Racquel Z. LeGeros |
| author_facet | Carlos A. Garrido Sonja E. Lobo Flávio M. Turíbio Racquel Z. LeGeros |
| author_sort | Carlos A. Garrido |
| collection | DOAJ |
| description | BCP are considered the most promising biomaterials for bone reconstruction. This study aims at analyzing the outcomes of patients who received BCP as bone substitutes in orthopaedic surgeries. Sixty-six patients were categorized according to the etiology and morphology of the bone defects and received scores after clinical and radiographic evaluations. The final results corresponded to the combination of both parameters and varied from 5 (excellent result) to 2 or lower (poor result). Most of the patients who presented cavitary defects or bone losses due to prosthesis placement or revision, osteotomies, or arthrodesis showed good results, and some of them excellent results. However, patients with segmental defects equal or larger than 3 cm in length were classified as moderate results. This study established clinical parameters where the BCP alone can successfully support the osteogenic process and where the association with other tissue engineering strategies may be considered. |
| format | Article |
| id | doaj-art-e6be511d65ab42ebb63faa128c198765 |
| institution | Kabale University |
| issn | 1687-8787 1687-8795 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomaterials |
| spelling | doaj-art-e6be511d65ab42ebb63faa128c1987652025-08-20T03:26:00ZengWileyInternational Journal of Biomaterials1687-87871687-87952011-01-01201110.1155/2011/129727129727Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical OutcomesCarlos A. Garrido0Sonja E. Lobo1Flávio M. Turíbio2Racquel Z. LeGeros3Department of Orthopaedic Surgery, Hospital São Bento Cardioclinica Ltda., Rua Crucis 50, 30.360-290 Belo Horizonte, Minas Gerais, BrazilDepartment of Morphology, Federal University of São Paulo, Rua Botucatu 740, 04023-900 São Paulo, BrazilDepartment of Orthopedic Surgery, Federal University of São Paulo, Rua Borges Lagoa 783, 04038-032 São Paulo, BrazilDepartment of Biomaterials and Biomimetics, New York University College of Dentistry, 345 East 24th Street, New York, NY 10010, USABCP are considered the most promising biomaterials for bone reconstruction. This study aims at analyzing the outcomes of patients who received BCP as bone substitutes in orthopaedic surgeries. Sixty-six patients were categorized according to the etiology and morphology of the bone defects and received scores after clinical and radiographic evaluations. The final results corresponded to the combination of both parameters and varied from 5 (excellent result) to 2 or lower (poor result). Most of the patients who presented cavitary defects or bone losses due to prosthesis placement or revision, osteotomies, or arthrodesis showed good results, and some of them excellent results. However, patients with segmental defects equal or larger than 3 cm in length were classified as moderate results. This study established clinical parameters where the BCP alone can successfully support the osteogenic process and where the association with other tissue engineering strategies may be considered.http://dx.doi.org/10.1155/2011/129727 |
| spellingShingle | Carlos A. Garrido Sonja E. Lobo Flávio M. Turíbio Racquel Z. LeGeros Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes International Journal of Biomaterials |
| title | Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes |
| title_full | Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes |
| title_fullStr | Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes |
| title_full_unstemmed | Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes |
| title_short | Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes |
| title_sort | biphasic calcium phosphate bioceramics for orthopaedic reconstructions clinical outcomes |
| url | http://dx.doi.org/10.1155/2011/129727 |
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