Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression
Abstract Background Anterior clinoid process metastases are rare. We present an unusual case of anterior clinoid process metastasis with sudden deterioration of visual function requiring emergency optic nerve decompression, resulting in visual recovery. Case presentation We report the case of a 41-y...
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| Language: | English |
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SpringerOpen
2025-02-01
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| Series: | Egyptian Journal of Neurosurgery |
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| Online Access: | https://doi.org/10.1186/s41984-025-00371-3 |
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| author | Marta Rico-Pereira Fernando Muñoz-Hernández |
| author_facet | Marta Rico-Pereira Fernando Muñoz-Hernández |
| author_sort | Marta Rico-Pereira |
| collection | DOAJ |
| description | Abstract Background Anterior clinoid process metastases are rare. We present an unusual case of anterior clinoid process metastasis with sudden deterioration of visual function requiring emergency optic nerve decompression, resulting in visual recovery. Case presentation We report the case of a 41-year-old male patient with a diagnosis of radius leiomyosarcoma, who underwent surgery in 2014, with bone and lung metastases, who had been treated with chemotherapy and appeared to have the disease controlled at his last follow-up. 6 years later, he developed a one month history of progressive unilateral loss of visual acuity and visual field defect (initially quadrantanopia that progressed to nasal hemianopia). Brain imaging showed a contrast-enhancing lesion affecting the left anterior clinoid process with extension to the cavernous sinus and sphenoid sinus, causing compression of the left optic nerve. Although the lesion could have suggested a meningioma given the location, in the context of the patient’s oncological history, the diagnosis of metastasis was considered more likely. The patient was admitted to hospital and, during the hospital stay, developed sudden left retro-orbital pain progressing to left amaurosis over approximately 8 h. Urgent surgery was performed: a pterional craniotomy with partial tumor removal and optic nerve decompression with extradural anterior clinoidectomy. After surgery, the patient had an immediate but partial improvement in visual acuity and in the visual field defect. Conclusions Metastasis to the anterior clinoid process is very uncommon, with only one case previously reported in the literature. In cases of visual impairment, symptoms may deteriorate rapidly to complete loss of vision, so urgent decompressive surgery of the optic nerve may be indicated to recover visual function, although recovery may be partial. |
| format | Article |
| id | doaj-art-e6bbc44a3c77445288f23b634bbb9a2c |
| institution | Kabale University |
| issn | 2520-8225 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SpringerOpen |
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| series | Egyptian Journal of Neurosurgery |
| spelling | doaj-art-e6bbc44a3c77445288f23b634bbb9a2c2025-02-09T12:25:22ZengSpringerOpenEgyptian Journal of Neurosurgery2520-82252025-02-014011610.1186/s41984-025-00371-3Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompressionMarta Rico-Pereira0Fernando Muñoz-Hernández1Department of Neurosurgery, Hospital Santa Creu I Sant PauDepartment of Neurosurgery, Hospital Santa Creu I Sant PauAbstract Background Anterior clinoid process metastases are rare. We present an unusual case of anterior clinoid process metastasis with sudden deterioration of visual function requiring emergency optic nerve decompression, resulting in visual recovery. Case presentation We report the case of a 41-year-old male patient with a diagnosis of radius leiomyosarcoma, who underwent surgery in 2014, with bone and lung metastases, who had been treated with chemotherapy and appeared to have the disease controlled at his last follow-up. 6 years later, he developed a one month history of progressive unilateral loss of visual acuity and visual field defect (initially quadrantanopia that progressed to nasal hemianopia). Brain imaging showed a contrast-enhancing lesion affecting the left anterior clinoid process with extension to the cavernous sinus and sphenoid sinus, causing compression of the left optic nerve. Although the lesion could have suggested a meningioma given the location, in the context of the patient’s oncological history, the diagnosis of metastasis was considered more likely. The patient was admitted to hospital and, during the hospital stay, developed sudden left retro-orbital pain progressing to left amaurosis over approximately 8 h. Urgent surgery was performed: a pterional craniotomy with partial tumor removal and optic nerve decompression with extradural anterior clinoidectomy. After surgery, the patient had an immediate but partial improvement in visual acuity and in the visual field defect. Conclusions Metastasis to the anterior clinoid process is very uncommon, with only one case previously reported in the literature. In cases of visual impairment, symptoms may deteriorate rapidly to complete loss of vision, so urgent decompressive surgery of the optic nerve may be indicated to recover visual function, although recovery may be partial.https://doi.org/10.1186/s41984-025-00371-3Anterior clinoid processSkull base metástasisAnterior clinoidectomyVisual lossOptic nerve |
| spellingShingle | Marta Rico-Pereira Fernando Muñoz-Hernández Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression Egyptian Journal of Neurosurgery Anterior clinoid process Skull base metástasis Anterior clinoidectomy Visual loss Optic nerve |
| title | Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression |
| title_full | Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression |
| title_fullStr | Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression |
| title_full_unstemmed | Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression |
| title_short | Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression |
| title_sort | anterior clinoid process metastasis with sudden loss of vision role of emergency optic nerve decompression |
| topic | Anterior clinoid process Skull base metástasis Anterior clinoidectomy Visual loss Optic nerve |
| url | https://doi.org/10.1186/s41984-025-00371-3 |
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