Food oral immunotherapy

Abstract Food oral immunotherapy (OIT) is an option for the treatment of immunoglobin E (IgE)‐mediated food allergy that involves administering gradually increasing doses of an allergenic food over time (under medical supervision) with the goal of desensitizing an individual to the food allergen. Cu...

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Main Authors: Mary McHenry, Philippe Bégin, Edmond S. Chan, Meriem Latrous, Harold Kim
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Allergy, Asthma & Clinical Immunology
Online Access:https://doi.org/10.1186/s13223-025-00948-5
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author Mary McHenry
Philippe Bégin
Edmond S. Chan
Meriem Latrous
Harold Kim
author_facet Mary McHenry
Philippe Bégin
Edmond S. Chan
Meriem Latrous
Harold Kim
author_sort Mary McHenry
collection DOAJ
description Abstract Food oral immunotherapy (OIT) is an option for the treatment of immunoglobin E (IgE)‐mediated food allergy that involves administering gradually increasing doses of an allergenic food over time (under medical supervision) with the goal of desensitizing an individual to the food allergen. Current Canadian clinical practice guidelines for OIT recommend this form of therapy as an option in patients with food allergy. The intervention should be prioritized in the infant and toddler population, in which it is particularly well tolerated and can lead to sustained unresponsiveness (also sometimes referred to as remission). In this article, we provide an overview of OIT and discuss the role non-allergist clinicians can play in caring for patients undergoing OIT.
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series Allergy, Asthma & Clinical Immunology
spelling doaj-art-e6ba99d5a5c8459c95ff6985622295de2025-08-20T02:03:36ZengBMCAllergy, Asthma & Clinical Immunology1710-14922025-02-0120S311310.1186/s13223-025-00948-5Food oral immunotherapyMary McHenry0Philippe Bégin1Edmond S. Chan2Meriem Latrous3Harold Kim4Pediatric Allergy & Clinical Immunology, Dalhousie University/IWK Health CentreDivision of Clinical Immunology and Allergy, Department of Medicine, Université de MontréalDivision of Allergy, Department of Pediatrics, University of British Columbia, British Columbia Children’s HospitalDivision of Infectious Diseases, Immunology, and Allergy, Department of Pediatrics, Children’s Hospital of Eastern OntarioDivision of Clinical Immunology & Allergy, Department of Medicine, McMaster UniversityAbstract Food oral immunotherapy (OIT) is an option for the treatment of immunoglobin E (IgE)‐mediated food allergy that involves administering gradually increasing doses of an allergenic food over time (under medical supervision) with the goal of desensitizing an individual to the food allergen. Current Canadian clinical practice guidelines for OIT recommend this form of therapy as an option in patients with food allergy. The intervention should be prioritized in the infant and toddler population, in which it is particularly well tolerated and can lead to sustained unresponsiveness (also sometimes referred to as remission). In this article, we provide an overview of OIT and discuss the role non-allergist clinicians can play in caring for patients undergoing OIT.https://doi.org/10.1186/s13223-025-00948-5
spellingShingle Mary McHenry
Philippe Bégin
Edmond S. Chan
Meriem Latrous
Harold Kim
Food oral immunotherapy
Allergy, Asthma & Clinical Immunology
title Food oral immunotherapy
title_full Food oral immunotherapy
title_fullStr Food oral immunotherapy
title_full_unstemmed Food oral immunotherapy
title_short Food oral immunotherapy
title_sort food oral immunotherapy
url https://doi.org/10.1186/s13223-025-00948-5
work_keys_str_mv AT marymchenry foodoralimmunotherapy
AT philippebegin foodoralimmunotherapy
AT edmondschan foodoralimmunotherapy
AT meriemlatrous foodoralimmunotherapy
AT haroldkim foodoralimmunotherapy