EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway

EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway

Candida albicans is a fungal pathobiont colonizing mucosal surfaces of the human body, including the oral cavity. Under certain predisposing conditions, C. albicans invades mucosal tissues activating EGFR-MAPK signalling pathways in epithelial cells via the action of its peptide toxin candidalysin....

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Bibliographic Details
Main Authors: Ruth E. Dickenson, Aize Pellon, Nicole O. Ponde, Olivia Hepworth, Lydia F. Daniels Gatward, Julian R. Naglik, David L. Moyes
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Virulence
Subjects:
EGR1
Candida
epithelial cell
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2024.2435374
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