Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem Cells
The academic researches and clinical applications in recent years found interest in induced pluripotent stem cells (iPSCs-) based regenerative medicine due to their pluripotency able to differentiate into any cell types in the body without using embryo. However, it is limited in generating iPSCs fro...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2016/9762465 |
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| _version_ | 1832561050069762048 |
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| author | Jung-Hwan Lee Seog-Jin Seo |
| author_facet | Jung-Hwan Lee Seog-Jin Seo |
| author_sort | Jung-Hwan Lee |
| collection | DOAJ |
| description | The academic researches and clinical applications in recent years found interest in induced pluripotent stem cells (iPSCs-) based regenerative medicine due to their pluripotency able to differentiate into any cell types in the body without using embryo. However, it is limited in generating iPSCs from adult somatic cells and use of these cells due to the low stem cell potency and donor site morbidity. In biomedical applications, particularly, dental tissue-derived iPSCs have been getting attention as a type of alternative sources for regenerating damaged tissues due to high potential of stem cell characteristics, easy accessibility and attainment, and their ectomesenchymal origin, which allow them to have potential for nerve, vessel, and dental tissue regeneration. This paper will cover the overview of dental tissue-derived iPSCs and their application with their advantages and drawbacks. |
| format | Article |
| id | doaj-art-e6b6f9b0c46a44a6a8023a9225e735f4 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-e6b6f9b0c46a44a6a8023a9225e735f42025-02-03T01:26:13ZengWileyStem Cells International1687-966X1687-96782016-01-01201610.1155/2016/97624659762465Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem CellsJung-Hwan Lee0Seog-Jin Seo1Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 330-714, Republic of KoreaInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan 330-714, Republic of KoreaThe academic researches and clinical applications in recent years found interest in induced pluripotent stem cells (iPSCs-) based regenerative medicine due to their pluripotency able to differentiate into any cell types in the body without using embryo. However, it is limited in generating iPSCs from adult somatic cells and use of these cells due to the low stem cell potency and donor site morbidity. In biomedical applications, particularly, dental tissue-derived iPSCs have been getting attention as a type of alternative sources for regenerating damaged tissues due to high potential of stem cell characteristics, easy accessibility and attainment, and their ectomesenchymal origin, which allow them to have potential for nerve, vessel, and dental tissue regeneration. This paper will cover the overview of dental tissue-derived iPSCs and their application with their advantages and drawbacks.http://dx.doi.org/10.1155/2016/9762465 |
| spellingShingle | Jung-Hwan Lee Seog-Jin Seo Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem Cells Stem Cells International |
| title | Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem Cells |
| title_full | Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem Cells |
| title_fullStr | Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem Cells |
| title_full_unstemmed | Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem Cells |
| title_short | Biomedical Application of Dental Tissue-Derived Induced Pluripotent Stem Cells |
| title_sort | biomedical application of dental tissue derived induced pluripotent stem cells |
| url | http://dx.doi.org/10.1155/2016/9762465 |
| work_keys_str_mv | AT junghwanlee biomedicalapplicationofdentaltissuederivedinducedpluripotentstemcells AT seogjinseo biomedicalapplicationofdentaltissuederivedinducedpluripotentstemcells |