Deep learning guided high-throughput virtual screening for in vitro antibody maturation
Antibody affinity maturation is a crucial step in therapeutic antibody discovery. In this study, we present a virtual screening pipeline that integrates protein docking with deep learning-based structural prediction to identify antibody mutants with enhanced binding affinity for the antigen sST2. By...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2025-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2025/25/bioconf_icbb2025_03017.pdf |
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