Opportunities for early diagnostics of contemporary obstetric sepsis
Aim: to objectively assess potential for early generalized postpartum infection diagnostics prior to the onset of irreversible organ changes based on a retrospective analysis.Materials and Methods. Сlinical and laboratory forensic medical data were examined by analysing 29 cases of severe maternal o...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2021-05-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/966 |
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| author | V. F. Bezhenar V. A. Shapkaitz I. A. Dobrovolskaya E. A. Rukoyatkina I. M. Nesterov |
| author_facet | V. F. Bezhenar V. A. Shapkaitz I. A. Dobrovolskaya E. A. Rukoyatkina I. M. Nesterov |
| author_sort | V. F. Bezhenar |
| collection | DOAJ |
| description | Aim: to objectively assess potential for early generalized postpartum infection diagnostics prior to the onset of irreversible organ changes based on a retrospective analysis.Materials and Methods. Сlinical and laboratory forensic medical data were examined by analysing 29 cases of severe maternal outcomes coupled to sepsis: including 17 «near miss» and 12 deceased patients (maternal mortality). The control group consisted of 30 patients who had chorioamnionitis in labor and successfully completed pregnancy. Statistical data analysis was carried out by using nonparametric statistics by creating conjugacy tables and assessing a relationship between parameters with Pearson χ2 distribution.Results. There were found significant differences in rate of some symptoms in both groups. Patients with severe maternal outcomes vs. control group were significantly more likely to develop hyperthermia ≥ 38.0 °C or hypothermia ≤ 36.0 °C, hectic fever, leukocytosis ≥ 12×109/L or leukopenia ≤ 4×109/L before the end of pregnancy; after pregnancy, persistent subfebrility, febrility or hypothermia, hectic fever, multiple-organ failure syndrome (PON), as well as uterine subinvolution and abnormal discharge from the genital tract were observed.Conclusion. Early identification of recognized symptoms of systemic inflammatory response syndrome and PON allows to properly assess severity of patient condition, taking into account the risk of generalized infection, contributes to making correct diagnosis and timely implementation of adequate organizational and therapeutic measures. |
| format | Article |
| id | doaj-art-e6b2813f05104ec6b4d28dc2d4dea118 |
| institution | Kabale University |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2021-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-e6b2813f05104ec6b4d28dc2d4dea1182025-08-20T03:39:36ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942021-05-0115212113110.17749/2313-7347/ob.gyn.rep.2021.183636Opportunities for early diagnostics of contemporary obstetric sepsisV. F. Bezhenar0V. A. Shapkaitz1I. A. Dobrovolskaya2E. A. Rukoyatkina3I. M. Nesterov4Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian FederationPavlov First Saint Petersburg State Medical University, Health Ministry of Russian Federation; Saint Petersburg Maternity Hospital № 16Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian FederationSaint Petersburg Maternity Hospital № 16Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian FederationAim: to objectively assess potential for early generalized postpartum infection diagnostics prior to the onset of irreversible organ changes based on a retrospective analysis.Materials and Methods. Сlinical and laboratory forensic medical data were examined by analysing 29 cases of severe maternal outcomes coupled to sepsis: including 17 «near miss» and 12 deceased patients (maternal mortality). The control group consisted of 30 patients who had chorioamnionitis in labor and successfully completed pregnancy. Statistical data analysis was carried out by using nonparametric statistics by creating conjugacy tables and assessing a relationship between parameters with Pearson χ2 distribution.Results. There were found significant differences in rate of some symptoms in both groups. Patients with severe maternal outcomes vs. control group were significantly more likely to develop hyperthermia ≥ 38.0 °C or hypothermia ≤ 36.0 °C, hectic fever, leukocytosis ≥ 12×109/L or leukopenia ≤ 4×109/L before the end of pregnancy; after pregnancy, persistent subfebrility, febrility or hypothermia, hectic fever, multiple-organ failure syndrome (PON), as well as uterine subinvolution and abnormal discharge from the genital tract were observed.Conclusion. Early identification of recognized symptoms of systemic inflammatory response syndrome and PON allows to properly assess severity of patient condition, taking into account the risk of generalized infection, contributes to making correct diagnosis and timely implementation of adequate organizational and therapeutic measures.https://www.gynecology.su/jour/article/view/966pregnancypredictors of sepsisnear missmaternal mortalitychorioamnionitis |
| spellingShingle | V. F. Bezhenar V. A. Shapkaitz I. A. Dobrovolskaya E. A. Rukoyatkina I. M. Nesterov Opportunities for early diagnostics of contemporary obstetric sepsis Акушерство, гинекология и репродукция pregnancy predictors of sepsis near miss maternal mortality chorioamnionitis |
| title | Opportunities for early diagnostics of contemporary obstetric sepsis |
| title_full | Opportunities for early diagnostics of contemporary obstetric sepsis |
| title_fullStr | Opportunities for early diagnostics of contemporary obstetric sepsis |
| title_full_unstemmed | Opportunities for early diagnostics of contemporary obstetric sepsis |
| title_short | Opportunities for early diagnostics of contemporary obstetric sepsis |
| title_sort | opportunities for early diagnostics of contemporary obstetric sepsis |
| topic | pregnancy predictors of sepsis near miss maternal mortality chorioamnionitis |
| url | https://www.gynecology.su/jour/article/view/966 |
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