The moderating role of COMT gene rs4680 polymorphism between maladaptive metacognitive beliefs and negative symptoms in patients with schizophrenia

The moderating role of COMT gene rs4680 polymorphism between maladaptive metacognitive beliefs and negative symptoms in patients with schizophrenia

Abstract Background Although the positive association between impairments in metacognitive capacity and negative symptoms in people with schizophrenia spectrum disorders is widely evidenced in the literature, the explaining mechanisms of this association are still less known and poorly understood. T...

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Main Authors: Feten Fekih-Romdhane, Georges Kerbage, Nagham Hachem, Michelle El Murr, Georges Haddad, Alexandre Andrade Loch, Rony Abou Khalil, Elissar El Hayek, Souheil Hallit
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Psychiatry
Subjects:
Metacognition
Negative symptoms
COMT gene
rs4680
Schizophrenia
Online Access:https://doi.org/10.1186/s12888-024-06275-0
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