Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy Adults

Introduction: This study aimed to determine the glycemic index (GI)/glycemic load (GL) of three crackers made with different flours. A control cracker (CC), with a 30% <i>w</i>/<i>w</i> substitution of wheat by whole wheat flour (WWC) and with a 30% <i>w</i>/<i...

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Main Authors: Emilia Papakonstantinou, Vasilis Alsab, Foteini Lympaki, Sofia Chanioti, Marianna Giannoglou, George Katsaros
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/91/1/303
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author Emilia Papakonstantinou
Vasilis Alsab
Foteini Lympaki
Sofia Chanioti
Marianna Giannoglou
George Katsaros
author_facet Emilia Papakonstantinou
Vasilis Alsab
Foteini Lympaki
Sofia Chanioti
Marianna Giannoglou
George Katsaros
author_sort Emilia Papakonstantinou
collection DOAJ
description Introduction: This study aimed to determine the glycemic index (GI)/glycemic load (GL) of three crackers made with different flours. A control cracker (CC), with a 30% <i>w</i>/<i>w</i> substitution of wheat by whole wheat flour (WWC) and with a 30% <i>w</i>/<i>w</i> substitution of wheat by sunflower seed flour (SFC), differing significantly in protein and fiber content, is compared to the reference D-glucose drink. Methods: In a randomized, controlled, crossover design, 11 healthy participants (23.5 (1) years; seven women; BMI 23 (1) kg/m<sup>2</sup>) were randomly assigned to receive three cracker meals (CC, WWC, and SFC), all containing 50 g of available carbohydrates and 50 g of D-glucose as a reference drink. Results: SFC provided medium GI, low GL values (GI: 56 on glucose scale, GL: 6 per serving), whereas WWC and CC provided high GI, medium GL values (GI: 77 and 90 on glucose scale, respectively; GL: 11 and 12 per serving, respectively). Both SFC and WWC provided lower postprandial glucose concentrations, lower glucose excursions, and lower peak glucose values compared to glucose and CC. All crackers were pleasurable and increased satiety when compared to glucose, without any significant differences between them. Conclusion: SFC and WWC, regardless of soluble fiber and/or protein content, attenuated postprandial glycemic response and improved subjective satiety, which may offer advantages for body weight and glycemic control. This trial was registered at Clinicaltrials.gov: NCT05702372.
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spelling doaj-art-e6a8e587b8194e1786fc4127fd3f62cc2025-08-20T02:43:06ZengMDPI AGProceedings2504-39002024-02-0191130310.3390/proceedings2023091303Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy AdultsEmilia Papakonstantinou0Vasilis Alsab1Foteini Lympaki2Sofia Chanioti3Marianna Giannoglou4George Katsaros5Laboratory of Dietetics and Quality of Life, Department of Food Science and Human Nutrition, Agricultural University of Athens, 11855 Athens, GreeceLaboratory of Dietetics and Quality of Life, Department of Food Science and Human Nutrition, Agricultural University of Athens, 11855 Athens, GreeceLaboratory of Dietetics and Quality of Life, Department of Food Science and Human Nutrition, Agricultural University of Athens, 11855 Athens, GreeceInstitute of Technology of Agricultural Products, Hellenic Agricultural Organization “DEMETER”, Attiki, 14123 Lykovrisi, GreeceInstitute of Technology of Agricultural Products, Hellenic Agricultural Organization “DEMETER”, Attiki, 14123 Lykovrisi, GreeceInstitute of Technology of Agricultural Products, Hellenic Agricultural Organization “DEMETER”, Attiki, 14123 Lykovrisi, GreeceIntroduction: This study aimed to determine the glycemic index (GI)/glycemic load (GL) of three crackers made with different flours. A control cracker (CC), with a 30% <i>w</i>/<i>w</i> substitution of wheat by whole wheat flour (WWC) and with a 30% <i>w</i>/<i>w</i> substitution of wheat by sunflower seed flour (SFC), differing significantly in protein and fiber content, is compared to the reference D-glucose drink. Methods: In a randomized, controlled, crossover design, 11 healthy participants (23.5 (1) years; seven women; BMI 23 (1) kg/m<sup>2</sup>) were randomly assigned to receive three cracker meals (CC, WWC, and SFC), all containing 50 g of available carbohydrates and 50 g of D-glucose as a reference drink. Results: SFC provided medium GI, low GL values (GI: 56 on glucose scale, GL: 6 per serving), whereas WWC and CC provided high GI, medium GL values (GI: 77 and 90 on glucose scale, respectively; GL: 11 and 12 per serving, respectively). Both SFC and WWC provided lower postprandial glucose concentrations, lower glucose excursions, and lower peak glucose values compared to glucose and CC. All crackers were pleasurable and increased satiety when compared to glucose, without any significant differences between them. Conclusion: SFC and WWC, regardless of soluble fiber and/or protein content, attenuated postprandial glycemic response and improved subjective satiety, which may offer advantages for body weight and glycemic control. This trial was registered at Clinicaltrials.gov: NCT05702372.https://www.mdpi.com/2504-3900/91/1/303crackerssunflower seed flourwhole wheat flourglycemic indexglycemic responses
spellingShingle Emilia Papakonstantinou
Vasilis Alsab
Foteini Lympaki
Sofia Chanioti
Marianna Giannoglou
George Katsaros
Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy Adults
Proceedings
crackers
sunflower seed flour
whole wheat flour
glycemic index
glycemic responses
title Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy Adults
title_full Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy Adults
title_fullStr Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy Adults
title_full_unstemmed Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy Adults
title_short Short-Term Effects of Crackers on Glycemic Index and Glycemic Responses: A Randomized Clinical Trial in Healthy Adults
title_sort short term effects of crackers on glycemic index and glycemic responses a randomized clinical trial in healthy adults
topic crackers
sunflower seed flour
whole wheat flour
glycemic index
glycemic responses
url https://www.mdpi.com/2504-3900/91/1/303
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AT foteinilympaki shorttermeffectsofcrackersonglycemicindexandglycemicresponsesarandomizedclinicaltrialinhealthyadults
AT sofiachanioti shorttermeffectsofcrackersonglycemicindexandglycemicresponsesarandomizedclinicaltrialinhealthyadults
AT mariannagiannoglou shorttermeffectsofcrackersonglycemicindexandglycemicresponsesarandomizedclinicaltrialinhealthyadults
AT georgekatsaros shorttermeffectsofcrackersonglycemicindexandglycemicresponsesarandomizedclinicaltrialinhealthyadults