Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D
In this paper, we conducted a numerical study to investigate the role of magnetic nanoparticles (MNPs) in the treatment of cancerous tissues in three dimensional. First, we considered the governing equations associated with this method. Next, we utilized the finite element method (FEM) and Comsol Mu...
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Semnan University
2024-12-01
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| Series: | Progress in Physics of Applied Materials |
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| Online Access: | https://ppam.semnan.ac.ir/article_9207_317fcf468acfc7a74029bf8179f690ba.pdf |
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| author | Abdol Jabbar Shokri Hamed Heidari |
| author_facet | Abdol Jabbar Shokri Hamed Heidari |
| author_sort | Abdol Jabbar Shokri |
| collection | DOAJ |
| description | In this paper, we conducted a numerical study to investigate the role of magnetic nanoparticles (MNPs) in the treatment of cancerous tissues in three dimensional. First, we considered the governing equations associated with this method. Next, we utilized the finite element method (FEM) and Comsol Multiphysics software package to calculate parameters such as temperature distribution, generated heat, and the fraction of damage in tumor and normal tissues over a 40-minute period. The applied frequencies and current in the coil were 150 and 300 kHz and 550 A, respectively. Our calculations revealed that the maximum temperatures of the tumor at frequencies of 150 and 300 kHz were 45.4 and 47 degrees, respectively. These temperatures are sufficient to destroy cancer cells. Furthermore, the comparison of results at 150 and 300 kHz frequencies demonstrated that parameters such as temperature, heat, and degradation rate increase with the increase of frequency. Additionally, we found that the tumor damage at the end of the process for frequencies of 150 and 300 kHz was 100% in the center of the tumor, but reduced to 63% and 75% at the border, respectively. |
| format | Article |
| id | doaj-art-e6a86d82957648448c4272a63d1480ca |
| institution | OA Journals |
| issn | 2783-4794 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Semnan University |
| record_format | Article |
| series | Progress in Physics of Applied Materials |
| spelling | doaj-art-e6a86d82957648448c4272a63d1480ca2025-08-20T01:50:42ZengSemnan UniversityProgress in Physics of Applied Materials2783-47942024-12-0151233010.22075/ppam.2024.34628.11079207Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3DAbdol Jabbar Shokri0Hamed Heidari1Department of Science, Payame Noor University, Sananda, IranDepartment of Physics, Varamin Region, Directorate of EducationIn this paper, we conducted a numerical study to investigate the role of magnetic nanoparticles (MNPs) in the treatment of cancerous tissues in three dimensional. First, we considered the governing equations associated with this method. Next, we utilized the finite element method (FEM) and Comsol Multiphysics software package to calculate parameters such as temperature distribution, generated heat, and the fraction of damage in tumor and normal tissues over a 40-minute period. The applied frequencies and current in the coil were 150 and 300 kHz and 550 A, respectively. Our calculations revealed that the maximum temperatures of the tumor at frequencies of 150 and 300 kHz were 45.4 and 47 degrees, respectively. These temperatures are sufficient to destroy cancer cells. Furthermore, the comparison of results at 150 and 300 kHz frequencies demonstrated that parameters such as temperature, heat, and degradation rate increase with the increase of frequency. Additionally, we found that the tumor damage at the end of the process for frequencies of 150 and 300 kHz was 100% in the center of the tumor, but reduced to 63% and 75% at the border, respectively.https://ppam.semnan.ac.ir/article_9207_317fcf468acfc7a74029bf8179f690ba.pdfmagnetic hyperthermiamagnetic nanoparticlesbreast cancersimulationcomsol multiphysics |
| spellingShingle | Abdol Jabbar Shokri Hamed Heidari Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D Progress in Physics of Applied Materials magnetic hyperthermia magnetic nanoparticles breast cancer simulation comsol multiphysics |
| title | Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D |
| title_full | Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D |
| title_fullStr | Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D |
| title_full_unstemmed | Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D |
| title_short | Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D |
| title_sort | numerical study of the role of nanoparticles in breast tumor treatment in 3d |
| topic | magnetic hyperthermia magnetic nanoparticles breast cancer simulation comsol multiphysics |
| url | https://ppam.semnan.ac.ir/article_9207_317fcf468acfc7a74029bf8179f690ba.pdf |
| work_keys_str_mv | AT abdoljabbarshokri numericalstudyoftheroleofnanoparticlesinbreasttumortreatmentin3d AT hamedheidari numericalstudyoftheroleofnanoparticlesinbreasttumortreatmentin3d |