Advances in biological agents in the treatment of inflammatory bowel disease

Inflammatory bowel disease (IBD) is a chronic and progressive disease which is currently hard to cure. Traditional treatments, such as aminosalicylates, steroids and immunosuppressants, can only alleviate symptoms, but can’t prevent potential inflammation or change the disease progress. The applicat...

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Main Authors: Na LI, Mei YE
Format: Article
Language:zho
Published: Editorial Office of New Medicine 2022-08-01
Series:Yixue xinzhi zazhi
Subjects:
Online Access:https://yxxz.whuznhmedj.com/storage/attach/2208/VO4xeZPbBch7s5ayeMl0E67uHzjTH7n8Zocmy2z5.pdf
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author Na LI
Mei YE
author_facet Na LI
Mei YE
author_sort Na LI
collection DOAJ
description Inflammatory bowel disease (IBD) is a chronic and progressive disease which is currently hard to cure. Traditional treatments, such as aminosalicylates, steroids and immunosuppressants, can only alleviate symptoms, but can’t prevent potential inflammation or change the disease progress. The application of biological agents represents a turning point in the treatment of IBD. With the expansion of research, an increasing number of new biological agents and small molecule drugs have entered various stages of clinical development. The chief focus of this review is the mechanisms of action and clinical trial data on emerging biological agents and small molecule drugs for the treatment of IBD.
format Article
id doaj-art-e6a4251add794b63aff4b0ca8ad11d17
institution OA Journals
issn 1004-5511
language zho
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publisher Editorial Office of New Medicine
record_format Article
series Yixue xinzhi zazhi
spelling doaj-art-e6a4251add794b63aff4b0ca8ad11d172025-08-20T02:35:25ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112022-08-0132431032010.12173/j.issn.1004-5511.2022040376344Advances in biological agents in the treatment of inflammatory bowel diseaseNa LIMei YEInflammatory bowel disease (IBD) is a chronic and progressive disease which is currently hard to cure. Traditional treatments, such as aminosalicylates, steroids and immunosuppressants, can only alleviate symptoms, but can’t prevent potential inflammation or change the disease progress. The application of biological agents represents a turning point in the treatment of IBD. With the expansion of research, an increasing number of new biological agents and small molecule drugs have entered various stages of clinical development. The chief focus of this review is the mechanisms of action and clinical trial data on emerging biological agents and small molecule drugs for the treatment of IBD.https://yxxz.whuznhmedj.com/storage/attach/2208/VO4xeZPbBch7s5ayeMl0E67uHzjTH7n8Zocmy2z5.pdfinflammatory bowel disease biological agents small molecule drugs therapeutics
spellingShingle Na LI
Mei YE
Advances in biological agents in the treatment of inflammatory bowel disease
Yixue xinzhi zazhi
inflammatory bowel disease
biological agents
small molecule drugs
therapeutics
title Advances in biological agents in the treatment of inflammatory bowel disease
title_full Advances in biological agents in the treatment of inflammatory bowel disease
title_fullStr Advances in biological agents in the treatment of inflammatory bowel disease
title_full_unstemmed Advances in biological agents in the treatment of inflammatory bowel disease
title_short Advances in biological agents in the treatment of inflammatory bowel disease
title_sort advances in biological agents in the treatment of inflammatory bowel disease
topic inflammatory bowel disease
biological agents
small molecule drugs
therapeutics
url https://yxxz.whuznhmedj.com/storage/attach/2208/VO4xeZPbBch7s5ayeMl0E67uHzjTH7n8Zocmy2z5.pdf
work_keys_str_mv AT nali advancesinbiologicalagentsinthetreatmentofinflammatoryboweldisease
AT meiye advancesinbiologicalagentsinthetreatmentofinflammatoryboweldisease