Noncanonical terpene cyclases for the biosynthesis of diterpenoids regulating chlamydospore formation in plant-associated Trichoderma

Noncanonical terpene cyclases for the biosynthesis of diterpenoids regulating chlamydospore formation in plant-associated Trichoderma

Abstract Terpene cyclases catalyze exquisite and complicated cyclization reactions to generate diverse terpenoid skeletons. Trichoderma fungi are important biocontrol agents, characteristic of producing complex bioactive tetracyclic diterpenoids named harzianes and trichodermanins, but their biosynt...

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Bibliographic Details
Main Authors: Min-Jie Yang, De-Sen Li, Hua-Qin Deng, Wen-Yuan Li, Xin-Yu Zheng, Jonathan Gershenzon, Xue-Mei Niu, Yan Liu, Sheng-Hong Li
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63055-4
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