Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks
As the global population continues to grow, so too does the demand for poultry meat. However, the concurrent increase in the prevalence of drug-resistant bacteria has stimulated interest in the search for alternatives to antibiotics in poultry and livestock agriculture. One potential strategy is the...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2024.1491039/full |
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| author | Aito Murakami Ayako Watanabe-Yanai Taketoshi Iwata Fu Namai Fu Namai Takashi Sato Tadashi Fujii Tadashi Fujii Tadashi Fujii Takumi Tochio Takumi Tochio Takumi Tochio Sutisa Khempaka Takeshi Shimosato Takeshi Shimosato |
| author_facet | Aito Murakami Ayako Watanabe-Yanai Taketoshi Iwata Fu Namai Fu Namai Takashi Sato Tadashi Fujii Tadashi Fujii Tadashi Fujii Takumi Tochio Takumi Tochio Takumi Tochio Sutisa Khempaka Takeshi Shimosato Takeshi Shimosato |
| author_sort | Aito Murakami |
| collection | DOAJ |
| description | As the global population continues to grow, so too does the demand for poultry meat. However, the concurrent increase in the prevalence of drug-resistant bacteria has stimulated interest in the search for alternatives to antibiotics in poultry and livestock agriculture. One potential strategy is the use of probiotics. In this study, we showed that prophylactic oral administration of Limosilactobacillus ingluviei C37 (LIC37) reduced Campylobacter jejuni colonization of the cecum in cage-raised chicks, without causing significant changes in the overall diversity of gut bacteria. Further, the abundance of Blautia, another genus of probiotic bacteria, increased in the gastrointestinal tract following ingestion of LIC37 by chicks. These findings suggest that LIC37 could potentially be used as a novel probiotic agent against C. jejuni in livestock production. |
| format | Article |
| id | doaj-art-e6a281973d4d488d87ea43a1936813dd |
| institution | Kabale University |
| issn | 1664-302X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj-art-e6a281973d4d488d87ea43a1936813dd2024-11-28T06:33:37ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2024-11-011510.3389/fmicb.2024.14910391491039Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicksAito Murakami0Ayako Watanabe-Yanai1Taketoshi Iwata2Fu Namai3Fu Namai4Takashi Sato5Tadashi Fujii6Tadashi Fujii7Tadashi Fujii8Takumi Tochio9Takumi Tochio10Takumi Tochio11Sutisa Khempaka12Takeshi Shimosato13Takeshi Shimosato14Graduate School of Medicine, Science and Technology, Shinshu University, Nagano, JapanDivision of Zoonosis Research, National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, JapanDivision of Zoonosis Research, National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, JapanFood and Feed Immunology Group, Laboratory of Animal Food Function, Graduate School of Agricultural Science, Tohoku University, Sendai, JapanLivestock Immunology Unit, International Education and Research Center for Food and Agricultural Immunology (CFAI), Graduate School of Agricultural Science, Tohoku University, Sendai, JapanDepartment of Biomolecular Innovation, Institute for Biomedical Sciences, Shinshu University, Kamiina, JapanDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake, JapanDepartment of Medical Research on Prebiotics and Probiotics, Fujita Health University, Toyoake, JapanBIOSIS Lab. Co., Ltd., Toyoake, JapanDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake, JapanDepartment of Medical Research on Prebiotics and Probiotics, Fujita Health University, Toyoake, JapanBIOSIS Lab. Co., Ltd., Toyoake, JapanSchool of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, ThailandDepartment of Biomolecular Innovation, Institute for Biomedical Sciences, Shinshu University, Kamiina, Japan0Institute for Aqua Regeneration, Shinshu University, Kamiina, JapanAs the global population continues to grow, so too does the demand for poultry meat. However, the concurrent increase in the prevalence of drug-resistant bacteria has stimulated interest in the search for alternatives to antibiotics in poultry and livestock agriculture. One potential strategy is the use of probiotics. In this study, we showed that prophylactic oral administration of Limosilactobacillus ingluviei C37 (LIC37) reduced Campylobacter jejuni colonization of the cecum in cage-raised chicks, without causing significant changes in the overall diversity of gut bacteria. Further, the abundance of Blautia, another genus of probiotic bacteria, increased in the gastrointestinal tract following ingestion of LIC37 by chicks. These findings suggest that LIC37 could potentially be used as a novel probiotic agent against C. jejuni in livestock production.https://www.frontiersin.org/articles/10.3389/fmicb.2024.1491039/fullLimosilactobacillus ingluviei C37Campylobacter jejunigut microbiotachickenprobiotics |
| spellingShingle | Aito Murakami Ayako Watanabe-Yanai Taketoshi Iwata Fu Namai Fu Namai Takashi Sato Tadashi Fujii Tadashi Fujii Tadashi Fujii Takumi Tochio Takumi Tochio Takumi Tochio Sutisa Khempaka Takeshi Shimosato Takeshi Shimosato Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks Frontiers in Microbiology Limosilactobacillus ingluviei C37 Campylobacter jejuni gut microbiota chicken probiotics |
| title | Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks |
| title_full | Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks |
| title_fullStr | Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks |
| title_full_unstemmed | Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks |
| title_short | Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks |
| title_sort | oral administration of limosilactobacillus ingluviei c37 inhibits campylobacter jejuni colonization in chicks |
| topic | Limosilactobacillus ingluviei C37 Campylobacter jejuni gut microbiota chicken probiotics |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2024.1491039/full |
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