Baseline gene expression in BALB/c and C57BL/6 peritoneal macrophages influences but does not dictate their functional phenotypes

Baseline gene expression in BALB/c and C57BL/6 peritoneal macrophages influences but does not dictate their functional phenotypes

Macrophages are effector cells of the immune system and essential modulators of immune responses. Different functional phenotypes of macrophages with specific roles in the response to stimuli have been described. The C57BL/6 and BALB/c mouse strains tend to selectively display distinct macrophage ac...

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Bibliographic Details
Main Authors: Carlos M. Restrepo, Alejandro Llanes, Lizzi Herrera, Esteban Ellis, Iliana Quintero, Patricia L. Fernández
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Experimental Biology and Medicine
Subjects:
macrophages
RNA-seq
BALB/c
C57BL/6
pathogen
Online Access:https://www.ebm-journal.org/articles/10.3389/ebm.2024.10377/full
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