PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity
Abstract Diabetes is a multi‐organ disease and diabetic cardiomyopathy can result in heart failure, which is a leading cause of morbidity and mortality in diabetic patients. In the liver, insulin resistance contributes to hyperglycaemia and hyperlipidaemia, which further worsens the metabolic profil...
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| Main Authors: | Mirko Völkers, Shirin Doroudgar, Nathalie Nguyen, Mathias H Konstandin, Pearl Quijada, Shabana Din, Luis Ornelas, Donna J Thuerauf, Natalie Gude, Kilian Friedrich, Stephan Herzig, Christopher C Glembotski, Mark A Sussman |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2013-10-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/emmm.201303183 |
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