Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential
Herbal medicines containing Passiflora species have been widely used to treat anxiety since ancient times. The species Passiflora incarnata L. is included in many Pharmacopoeias, and it is the most used species in food, cosmetic, and pharmaceutical industries. However, there are around 600 species o...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2020/6598434 |
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| author | Lyca R. da Fonseca Rafaele de A. Rodrigues Aline de S. Ramos Jefferson D. da Cruz José Luiz P. Ferreira Jefferson Rocha de A. Silva Ana Claudia F. Amaral |
| author_facet | Lyca R. da Fonseca Rafaele de A. Rodrigues Aline de S. Ramos Jefferson D. da Cruz José Luiz P. Ferreira Jefferson Rocha de A. Silva Ana Claudia F. Amaral |
| author_sort | Lyca R. da Fonseca |
| collection | DOAJ |
| description | Herbal medicines containing Passiflora species have been widely used to treat anxiety since ancient times. The species Passiflora incarnata L. is included in many Pharmacopoeias, and it is the most used species in food, cosmetic, and pharmaceutical industries. However, there are around 600 species of the genus Passiflora and probably other species that can be used safely. Thus, this article was based on a search into the uses of the main species of the genus Passiflora with anxiolytic activity and its main secondary metabolites and some pharmacological studies, patents, and registered products containing Passiflora. Furthermore, the Brazilian Regulatory Health Agency Datavisa, Medicines and Healthcare Products Regulatory Agency of the United Kingdom, and the European Medicines Agency websites were consulted. The results showed that Passiflora species have health benefits but clinical trials are still scarce. The complexity of Passiflora extracts creates challenges for the development of herbal medicines. P. incarnata is the most studied species of the genus and the most used in natural anxiolytic herbal medicine formulations. However, there are hundreds of Passiflora species potentially useful for medicinal and nutraceutical purposes that are still little explored. |
| format | Article |
| id | doaj-art-e6975f8d098746189a44ac8e30cc007d |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-e6975f8d098746189a44ac8e30cc007d2025-02-03T06:05:18ZengWileyThe Scientific World Journal2356-61401537-744X2020-01-01202010.1155/2020/65984346598434Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited PotentialLyca R. da Fonseca0Rafaele de A. Rodrigues1Aline de S. Ramos2Jefferson D. da Cruz3José Luiz P. Ferreira4Jefferson Rocha de A. Silva5Ana Claudia F. Amaral6Laboratory of Medicinal Plants and Derivatives, Department of Chemistry of Natural Products, Farmanguinhos, Fiocruz, Rio de Janeiro 21041-250, BrazilLaboratory of Medicinal Plants and Derivatives, Department of Chemistry of Natural Products, Farmanguinhos, Fiocruz, Rio de Janeiro 21041-250, BrazilLaboratory of Medicinal Plants and Derivatives, Department of Chemistry of Natural Products, Farmanguinhos, Fiocruz, Rio de Janeiro 21041-250, BrazilLaboratory of Medicinal Plants and Derivatives, Department of Chemistry of Natural Products, Farmanguinhos, Fiocruz, Rio de Janeiro 21041-250, BrazilLaboratory of Medicinal Plants and Derivatives, Department of Chemistry of Natural Products, Farmanguinhos, Fiocruz, Rio de Janeiro 21041-250, BrazilLaboratory of Chromatography, Department of Chemistry, Federal University of Amazonas, Manaus 69077-000, BrazilLaboratory of Medicinal Plants and Derivatives, Department of Chemistry of Natural Products, Farmanguinhos, Fiocruz, Rio de Janeiro 21041-250, BrazilHerbal medicines containing Passiflora species have been widely used to treat anxiety since ancient times. The species Passiflora incarnata L. is included in many Pharmacopoeias, and it is the most used species in food, cosmetic, and pharmaceutical industries. However, there are around 600 species of the genus Passiflora and probably other species that can be used safely. Thus, this article was based on a search into the uses of the main species of the genus Passiflora with anxiolytic activity and its main secondary metabolites and some pharmacological studies, patents, and registered products containing Passiflora. Furthermore, the Brazilian Regulatory Health Agency Datavisa, Medicines and Healthcare Products Regulatory Agency of the United Kingdom, and the European Medicines Agency websites were consulted. The results showed that Passiflora species have health benefits but clinical trials are still scarce. The complexity of Passiflora extracts creates challenges for the development of herbal medicines. P. incarnata is the most studied species of the genus and the most used in natural anxiolytic herbal medicine formulations. However, there are hundreds of Passiflora species potentially useful for medicinal and nutraceutical purposes that are still little explored.http://dx.doi.org/10.1155/2020/6598434 |
| spellingShingle | Lyca R. da Fonseca Rafaele de A. Rodrigues Aline de S. Ramos Jefferson D. da Cruz José Luiz P. Ferreira Jefferson Rocha de A. Silva Ana Claudia F. Amaral Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential The Scientific World Journal |
| title | Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential |
| title_full | Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential |
| title_fullStr | Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential |
| title_full_unstemmed | Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential |
| title_short | Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential |
| title_sort | herbal medicinal products from passiflora for anxiety an unexploited potential |
| url | http://dx.doi.org/10.1155/2020/6598434 |
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