Exercise Remodels Akkermansia-Associated Eicosanoid Metabolism to Alleviate Intestinal Senescence: Multi-Omics Insights

Exercise Remodels Akkermansia-Associated Eicosanoid Metabolism to Alleviate Intestinal Senescence: Multi-Omics Insights

Aerobic exercise mitigates age-related intestinal senescence through gut microbiota modulation, but the underlying mechanism has remained unclear. In this study, we performed 16S rRNA sequencing of gut contents from young, old, and old exercise C57BL/6J mice to assess exercise-induced alterations in...

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Bibliographic Details
Main Authors: Chunxia Yu, Xuanyu Liu, Yitong Li, Silin Li, Yating Huang, Sujuan Liu, Heng Shao, Yanna Shen, Li Fu
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microorganisms
Subjects:
exercise
aging
gut microbiota
eicosanoid metabolism
Online Access:https://www.mdpi.com/2076-2607/13/6/1379
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