The effect of Miya on skeletal muscle changes by regulating gut microbiota in rats with osteoarthritis through AMPK pathway

The effect of Miya on skeletal muscle changes by regulating gut microbiota in rats with osteoarthritis through AMPK pathway

Abstract Background The study aimed to explore whether Miya (MY), a kind of Clostridium butyricum, regulated osteoarthritis (OA) progression through adenosine 5’-monophosphate-activated protein kinase (AMPK) pathway. Methods The OA rats were orally given MY daily for 4 weeks and were intramuscularly...

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Bibliographic Details
Main Authors: Sen Wang, Zhengwei Duan, Zihua Li, Dong Yang, Hengli Lu, Yiwei Zhang, Yuesong Fu, Yonghao Guan, Guodong Li, Feng Qian, Tianyang Xu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Musculoskeletal Disorders
Subjects:
Miya
Osteoarthritis
AMPK
Gut microbiota
Online Access:https://doi.org/10.1186/s12891-024-08203-5
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