Preterm neonatal mortality in China during 2009-2018: A retrospective study.
In this retrospective analysis, we aimed to analyze the epidemic characteristics of neonatal mortality due to preterm birth at 28-36 weeks gestation in different regions from 2009 to 2018. Data were obtained from China's Under-5 Child Mortality Surveillance System (U5CMSS). The χ2 trend test, P...
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0260611&type=printable |
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| author | Xue Yu Chunhua He Yanping Wang Leni Kang Lei Miao Jian Chen Qihui Zhao Xiaona Huang Jun Zhu Juan Liang Qi Li Meixian Wang Hanmin Liu |
| author_facet | Xue Yu Chunhua He Yanping Wang Leni Kang Lei Miao Jian Chen Qihui Zhao Xiaona Huang Jun Zhu Juan Liang Qi Li Meixian Wang Hanmin Liu |
| author_sort | Xue Yu |
| collection | DOAJ |
| description | In this retrospective analysis, we aimed to analyze the epidemic characteristics of neonatal mortality due to preterm birth at 28-36 weeks gestation in different regions from 2009 to 2018. Data were obtained from China's Under-5 Child Mortality Surveillance System (U5CMSS). The χ2 trend test, Poisson regression and the Cochran-Mantel-Haenszel method were used in this study. We found that 51.3%, 42.0% and 44.5% of neonate deaths were preterm infants, and immaturity was mainly attributed to 60.1%, 64.1% and 69.5% of these deaths, in the eastern, central and western regions, respectively. The preterm neonatal mortality rate due to immaturity dropped from 149.2, 216.5 and 339.5 in 2009 to 47.4, 83.8 and 170.1 per 100 000 live births in 2018, giving an average annual decline rate of 12.1%, 11.6% and 6.3% in the eastern, central and western regions, respectively, during the studying period. The relative risk of preterm neonatal mortality due to immaturity were 1.3 and 2.3 for the central regions and western regions in 2009-2010, ascending to 2.2 and 3.9 in 2017-2018. The proportion of preterm neonatal deaths with a gestational age <32 weeks was highest among the eastern region. There were significantly more preterm neonatal infants who were not delivered at medical institutions in the western region than in the eastern and central regions. The preterm infant, especially with gestational age <32 weeks, should receive the most attention through enhanced policies and programs to improve child survival. Priority interventions should be region-specific, depending on the availability of economic and healthcare resources. |
| format | Article |
| id | doaj-art-e695ab69497c417bab2ca6d39309306d |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-e695ab69497c417bab2ca6d39309306d2025-08-20T03:15:43ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011612e026061110.1371/journal.pone.0260611Preterm neonatal mortality in China during 2009-2018: A retrospective study.Xue YuChunhua HeYanping WangLeni KangLei MiaoJian ChenQihui ZhaoXiaona HuangJun ZhuJuan LiangQi LiMeixian WangHanmin LiuIn this retrospective analysis, we aimed to analyze the epidemic characteristics of neonatal mortality due to preterm birth at 28-36 weeks gestation in different regions from 2009 to 2018. Data were obtained from China's Under-5 Child Mortality Surveillance System (U5CMSS). The χ2 trend test, Poisson regression and the Cochran-Mantel-Haenszel method were used in this study. We found that 51.3%, 42.0% and 44.5% of neonate deaths were preterm infants, and immaturity was mainly attributed to 60.1%, 64.1% and 69.5% of these deaths, in the eastern, central and western regions, respectively. The preterm neonatal mortality rate due to immaturity dropped from 149.2, 216.5 and 339.5 in 2009 to 47.4, 83.8 and 170.1 per 100 000 live births in 2018, giving an average annual decline rate of 12.1%, 11.6% and 6.3% in the eastern, central and western regions, respectively, during the studying period. The relative risk of preterm neonatal mortality due to immaturity were 1.3 and 2.3 for the central regions and western regions in 2009-2010, ascending to 2.2 and 3.9 in 2017-2018. The proportion of preterm neonatal deaths with a gestational age <32 weeks was highest among the eastern region. There were significantly more preterm neonatal infants who were not delivered at medical institutions in the western region than in the eastern and central regions. The preterm infant, especially with gestational age <32 weeks, should receive the most attention through enhanced policies and programs to improve child survival. Priority interventions should be region-specific, depending on the availability of economic and healthcare resources.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0260611&type=printable |
| spellingShingle | Xue Yu Chunhua He Yanping Wang Leni Kang Lei Miao Jian Chen Qihui Zhao Xiaona Huang Jun Zhu Juan Liang Qi Li Meixian Wang Hanmin Liu Preterm neonatal mortality in China during 2009-2018: A retrospective study. PLoS ONE |
| title | Preterm neonatal mortality in China during 2009-2018: A retrospective study. |
| title_full | Preterm neonatal mortality in China during 2009-2018: A retrospective study. |
| title_fullStr | Preterm neonatal mortality in China during 2009-2018: A retrospective study. |
| title_full_unstemmed | Preterm neonatal mortality in China during 2009-2018: A retrospective study. |
| title_short | Preterm neonatal mortality in China during 2009-2018: A retrospective study. |
| title_sort | preterm neonatal mortality in china during 2009 2018 a retrospective study |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0260611&type=printable |
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