Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran
ABSTRACT Background Given the influence of lifestyle on type 2 diabetes mellitus (T2DM), the present study aimed to investigate the association between physical activity (PA) intensity and T2DM among sedentary and active participants in the Zahedan Adult Cohort Study (ZACS), Iran. Methods This cross...
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Wiley
2025-04-01
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| Online Access: | https://doi.org/10.1002/hsr2.70658 |
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| author | Tahereh Dehdari Fariba Shahraki‐Sanavi Amir Nasiri Roghayeh Nouri Alireza A. Moghaddam Mahdi Mohammadi |
| author_facet | Tahereh Dehdari Fariba Shahraki‐Sanavi Amir Nasiri Roghayeh Nouri Alireza A. Moghaddam Mahdi Mohammadi |
| author_sort | Tahereh Dehdari |
| collection | DOAJ |
| description | ABSTRACT Background Given the influence of lifestyle on type 2 diabetes mellitus (T2DM), the present study aimed to investigate the association between physical activity (PA) intensity and T2DM among sedentary and active participants in the Zahedan Adult Cohort Study (ZACS), Iran. Methods This cross‐sectional study was conducted as part of the population‐based Persian Prospective Epidemiological Research Studies in Iran (Persian Cohort). The baseline data from the ZACS collected between 2015 and 2019 were utilized. A total of 10,004 adults aged 35–70 years were included in the analysis. Data were gathered through self‐reported questionnaires covering general information, socioeconomic status, sleep status, medical history, and PA. Anthropometric measurements and biochemical parameters were obtained from participants after a 12‐h fasting period. The data were analyzed using descriptive statistics, independent‐sample t‐test, chi‐square, and logistic regression tests in SPSS22. Results The study found that the majority of the 10,004 adult participants (81.2%) were sedentary, while only 18.8% were classified as active. Sedentary participants exhibited significantly higher mean values for various health markers, including age, education, sleep duration, weight, body mass index (BMI), and blood lipid levels, as well as higher prevalence of hypertension, cardiac conditions, and stroke compared to active participants. Additionally, 21.7% of the participants had T2DM, which was associated with older age, longer sleep duration, higher weight and BMI, and abnormal waist circumference. The prevalence of diabetes increased with higher BMI, from 4.8% in underweight to 27.1% in obese participants, and was 77% in sedentary individuals compared to 16% in active individuals. Even after adjusting for demographic factors (OR = 0.65, p < 0.001), lipid levels (odds ratio [OR] = 0.68, p = 0.001), sleep status (OR = 0.72, p = 0.001), and family history (OR = 0.66, p = 0.001), active individuals were found to have a significantly lower likelihood of being diabetic compared to their sedentary counterparts. Conclusions The findings revealed a clear association between sedentary lifestyles and an increased risk of T2DM. Physical inactivity was correlated with adverse health markers and an elevated incidence of T2DM, which was mitigated by an active lifestyle. These results underscore the importance of public health initiatives to promote PA as a critical strategy for diabetes prevention. |
| format | Article |
| id | doaj-art-e69502467f9242788c4d71c97bfd299c |
| institution | DOAJ |
| issn | 2398-8835 |
| language | English |
| publishDate | 2025-04-01 |
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| spelling | doaj-art-e69502467f9242788c4d71c97bfd299c2025-08-20T03:11:58ZengWileyHealth Science Reports2398-88352025-04-0184n/an/a10.1002/hsr2.70658Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, IranTahereh Dehdari0Fariba Shahraki‐Sanavi1Amir Nasiri2Roghayeh Nouri3Alireza A. Moghaddam4Mahdi Mohammadi5Department of Health Promotion and Education School of Public Health, Iran University of Medical Sciences Tehran IranHealth Promotion Research Center Zahedan University of Medical Sciences Zahedan IranDepartment of Health Promotion and Education School of Public Health, Iran University of Medical Sciences Tehran IranDepartment of Health Promotion and Education School of Public Health, Iran University of Medical Sciences Tehran IranHealth Promotion Research Center Zahedan University of Medical Sciences Zahedan IranHealth Promotion Research Center Zahedan University of Medical Sciences Zahedan IranABSTRACT Background Given the influence of lifestyle on type 2 diabetes mellitus (T2DM), the present study aimed to investigate the association between physical activity (PA) intensity and T2DM among sedentary and active participants in the Zahedan Adult Cohort Study (ZACS), Iran. Methods This cross‐sectional study was conducted as part of the population‐based Persian Prospective Epidemiological Research Studies in Iran (Persian Cohort). The baseline data from the ZACS collected between 2015 and 2019 were utilized. A total of 10,004 adults aged 35–70 years were included in the analysis. Data were gathered through self‐reported questionnaires covering general information, socioeconomic status, sleep status, medical history, and PA. Anthropometric measurements and biochemical parameters were obtained from participants after a 12‐h fasting period. The data were analyzed using descriptive statistics, independent‐sample t‐test, chi‐square, and logistic regression tests in SPSS22. Results The study found that the majority of the 10,004 adult participants (81.2%) were sedentary, while only 18.8% were classified as active. Sedentary participants exhibited significantly higher mean values for various health markers, including age, education, sleep duration, weight, body mass index (BMI), and blood lipid levels, as well as higher prevalence of hypertension, cardiac conditions, and stroke compared to active participants. Additionally, 21.7% of the participants had T2DM, which was associated with older age, longer sleep duration, higher weight and BMI, and abnormal waist circumference. The prevalence of diabetes increased with higher BMI, from 4.8% in underweight to 27.1% in obese participants, and was 77% in sedentary individuals compared to 16% in active individuals. Even after adjusting for demographic factors (OR = 0.65, p < 0.001), lipid levels (odds ratio [OR] = 0.68, p = 0.001), sleep status (OR = 0.72, p = 0.001), and family history (OR = 0.66, p = 0.001), active individuals were found to have a significantly lower likelihood of being diabetic compared to their sedentary counterparts. Conclusions The findings revealed a clear association between sedentary lifestyles and an increased risk of T2DM. Physical inactivity was correlated with adverse health markers and an elevated incidence of T2DM, which was mitigated by an active lifestyle. These results underscore the importance of public health initiatives to promote PA as a critical strategy for diabetes prevention.https://doi.org/10.1002/hsr2.70658Persian Cohortphysical activitytype 2 diabetes mellitus |
| spellingShingle | Tahereh Dehdari Fariba Shahraki‐Sanavi Amir Nasiri Roghayeh Nouri Alireza A. Moghaddam Mahdi Mohammadi Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran Health Science Reports Persian Cohort physical activity type 2 diabetes mellitus |
| title | Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran |
| title_full | Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran |
| title_fullStr | Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran |
| title_full_unstemmed | Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran |
| title_short | Relationship Between Physical Activity Levels and Type 2 Diabetes in Adults: Zahedan Adult Cohort Study, Iran |
| title_sort | relationship between physical activity levels and type 2 diabetes in adults zahedan adult cohort study iran |
| topic | Persian Cohort physical activity type 2 diabetes mellitus |
| url | https://doi.org/10.1002/hsr2.70658 |
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