Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different duration
The investigation was carried out on the white outbred female rats (n = 80) which were being under the influence of15 % solution of ethanol during pregnancy, from the first to the sixth months before its approach and on their viable posterity (n = 440). Anatomic, macro-microscopic and statistical me...
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Academician I.P. Pavlov First St. Petersburg State Medical University
2014-09-01
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| Series: | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
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| Online Access: | https://www.sci-notes.ru/jour/article/view/59 |
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| author | P. V. Pugach S. V. Kruglov |
| author_facet | P. V. Pugach S. V. Kruglov |
| author_sort | P. V. Pugach |
| collection | DOAJ |
| description | The investigation was carried out on the white outbred female rats (n = 80) which were being under the influence of15 % solution of ethanol during pregnancy, from the first to the sixth months before its approach and on their viable posterity (n = 440). Anatomic, macro-microscopic and statistical methods of research were used. Two periods of increasing mortality in rats were revealed: the first fell on 1st month of the experiment (mortality reached 25 %) and the second - on 5th and 6th months of the experiment when this indicator rose up to 10 %. The rats' pregnancy duration was increased: the most considerable prolongation of pregnancy (for 5 days) was determined in the female rats which were under the ethanol influence within six months before its approach. The pre-implantation mortality was prevailed in structure of the general antenatal mortality. The highest rates of these indicators were noted in the rats under the ethanol only during pregnancy, and also within two and six months before its approach. The maximum post-implantation mortality was registered in the animals which were affected by alcohol throughout five months before pregnancy. The indicator of mortality of posterity in the early post-natal period reached 100 % in posterity of female rats under the ethanol within three months before pregnancy and for its duration. |
| format | Article |
| id | doaj-art-e692375609a8469bae5736e58860af5b |
| institution | DOAJ |
| issn | 1607-4181 2541-8807 |
| language | Russian |
| publishDate | 2014-09-01 |
| publisher | Academician I.P. Pavlov First St. Petersburg State Medical University |
| record_format | Article |
| series | Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова |
| spelling | doaj-art-e692375609a8469bae5736e58860af5b2025-08-20T03:00:37ZrusAcademician I.P. Pavlov First St. Petersburg State Medical UniversityУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова1607-41812541-88072014-09-01213475010.24884/1607-4181-2014-21-3-47-5055Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different durationP. V. Pugach0S. V. Kruglov1Северо-Западный государственный медицинский университет имени И.И. МечниковаСеверо-Западный государственный медицинский университет имени И.И. МечниковаThe investigation was carried out on the white outbred female rats (n = 80) which were being under the influence of15 % solution of ethanol during pregnancy, from the first to the sixth months before its approach and on their viable posterity (n = 440). Anatomic, macro-microscopic and statistical methods of research were used. Two periods of increasing mortality in rats were revealed: the first fell on 1st month of the experiment (mortality reached 25 %) and the second - on 5th and 6th months of the experiment when this indicator rose up to 10 %. The rats' pregnancy duration was increased: the most considerable prolongation of pregnancy (for 5 days) was determined in the female rats which were under the ethanol influence within six months before its approach. The pre-implantation mortality was prevailed in structure of the general antenatal mortality. The highest rates of these indicators were noted in the rats under the ethanol only during pregnancy, and also within two and six months before its approach. The maximum post-implantation mortality was registered in the animals which were affected by alcohol throughout five months before pregnancy. The indicator of mortality of posterity in the early post-natal period reached 100 % in posterity of female rats under the ethanol within three months before pregnancy and for its duration.https://www.sci-notes.ru/jour/article/view/59этанолбеременностьсмертностьэмбрионплодноворожденныеethanolpregnancyembryofetusnewborn |
| spellingShingle | P. V. Pugach S. V. Kruglov Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different duration Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова этанол беременность смертность эмбрион плод новорожденные ethanol pregnancy embryo fetus newborn |
| title | Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different duration |
| title_full | Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different duration |
| title_fullStr | Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different duration |
| title_full_unstemmed | Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different duration |
| title_short | Adaptive possibilities, fertility and viability in posterity of female rats under the ethanol influence for the different duration |
| title_sort | adaptive possibilities fertility and viability in posterity of female rats under the ethanol influence for the different duration |
| topic | этанол беременность смертность эмбрион плод новорожденные ethanol pregnancy embryo fetus newborn |
| url | https://www.sci-notes.ru/jour/article/view/59 |
| work_keys_str_mv | AT pvpugach adaptivepossibilitiesfertilityandviabilityinposterityoffemaleratsundertheethanolinfluenceforthedifferentduration AT svkruglov adaptivepossibilitiesfertilityandviabilityinposterityoffemaleratsundertheethanolinfluenceforthedifferentduration |