Selective vulnerability of stellate cells to gut dysbiosis: neuroanatomical changes in the medial entorhinal cortex

IntroductionThe gut microbiota plays a critical role in regulating brain structure and function via the microbiota–gut–brain axis. Antibiotic-induced gut dysbiosis (AIGD) has been linked to neuroanatomical changes and cognitive deficits. However, its impact on neuronal morphology in layer II of the...

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Main Authors:	Ayishal B. Mydeen, Mohammed M. Nakhal, Faheema Nafees, Reem Almazrouei, Rasha Alkamali, Mahra Alsulaimi, Omar Aleissaee, Abdulrahman Alzaabi, Mohamed Alfahim, Hamad Almansoori, Shamsa BaniYas, Shaikha Al Houqani, Marim Elkashlan, Safa Shehab, Mohammad I. K. Hamad
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Neuroanatomy
Subjects:	medial entorhinal cortex microbiota-gut-brain axis dysbiosis stellate cells pyramidal island cells dendritic morphology
Online Access:	https://www.frontiersin.org/articles/10.3389/fnana.2025.1589287/full
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Selective vulnerability of stellate cells to gut dysbiosis: neuroanatomical changes in the medial entorhinal cortex

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