Autoimmune Uveitis. Review

For many years in ophthalmology there is a complex intractable problem associated with inflammation of the vascular membrane of the eye, the so-called uveitis. Experts around the world are trying to understand this heterogeneous pathology of the visual organ, in a short time, which can lead to a sha...

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Main Authors: A. N. Plekhanov, A. S. Fomina, O. P. Sverkunova, J. V. Ivanova
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2019-03-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/849
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author A. N. Plekhanov
A. S. Fomina
O. P. Sverkunova
J. V. Ivanova
author_facet A. N. Plekhanov
A. S. Fomina
O. P. Sverkunova
J. V. Ivanova
author_sort A. N. Plekhanov
collection DOAJ
description For many years in ophthalmology there is a complex intractable problem associated with inflammation of the vascular membrane of the eye, the so-called uveitis. Experts around the world are trying to understand this heterogeneous pathology of the visual organ, in a short time, which can lead to a sharp decrease in visual acuity, the development of severe complications and further disability. The number of patients with inflammation of the vascular tract is growing rapidly every year, the age is younger. The clinical picture of this pathology has changed slightly. Often began to manifest itself in two radically different directions. It proceeds as a sluggish form or vice versa manifests itself more aggressively with the rapid development of clinical manifestations in a short time. Currently, there is evidence of endogenous causes of uveitis.The article provides a review of the literature summarizing modern views on the problem of autoimmune uveitis. New factors affecting the etiology, pathogenesis of the disease, some aspects of therapy are considered. In addition, the main experimental models of autoimmune diseases of the vascular tract of the eye are analyzed.
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publisher Ophthalmology Publishing Group
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series Oftalʹmologiâ
spelling doaj-art-e67bbb5997a74677bd1b019cdc8ad2ca2025-08-20T02:56:17ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452019-03-0116151110.18008/1816-5095-2019-1-5-11485Autoimmune Uveitis. ReviewA. N. Plekhanov0A. S. Fomina1O. P. Sverkunova2J. V. Ivanova3Тhе Medical Institute of the Buryat State University The Clinical Hospital at the Ulan-Ude station Russian RailwaysТhе Medical Institute of the Buryat State University Baikal Branch “State Scientific and Production Center of Fishery”Тhе Medical Institute of the Buryat State University The Clinical Hospital at the Ulan-Ude station Russian RailwaysТhе Medical Institute of the Buryat State University The Republican Clinical Hospital named after N.A. Semashko.For many years in ophthalmology there is a complex intractable problem associated with inflammation of the vascular membrane of the eye, the so-called uveitis. Experts around the world are trying to understand this heterogeneous pathology of the visual organ, in a short time, which can lead to a sharp decrease in visual acuity, the development of severe complications and further disability. The number of patients with inflammation of the vascular tract is growing rapidly every year, the age is younger. The clinical picture of this pathology has changed slightly. Often began to manifest itself in two radically different directions. It proceeds as a sluggish form or vice versa manifests itself more aggressively with the rapid development of clinical manifestations in a short time. Currently, there is evidence of endogenous causes of uveitis.The article provides a review of the literature summarizing modern views on the problem of autoimmune uveitis. New factors affecting the etiology, pathogenesis of the disease, some aspects of therapy are considered. In addition, the main experimental models of autoimmune diseases of the vascular tract of the eye are analyzed.https://www.ophthalmojournal.com/opht/article/view/849autoimmune uveitisimmune systemautoimmune processexperimental modelimmunomodulator
spellingShingle A. N. Plekhanov
A. S. Fomina
O. P. Sverkunova
J. V. Ivanova
Autoimmune Uveitis. Review
Oftalʹmologiâ
autoimmune uveitis
immune system
autoimmune process
experimental model
immunomodulator
title Autoimmune Uveitis. Review
title_full Autoimmune Uveitis. Review
title_fullStr Autoimmune Uveitis. Review
title_full_unstemmed Autoimmune Uveitis. Review
title_short Autoimmune Uveitis. Review
title_sort autoimmune uveitis review
topic autoimmune uveitis
immune system
autoimmune process
experimental model
immunomodulator
url https://www.ophthalmojournal.com/opht/article/view/849
work_keys_str_mv AT anplekhanov autoimmuneuveitisreview
AT asfomina autoimmuneuveitisreview
AT opsverkunova autoimmuneuveitisreview
AT jvivanova autoimmuneuveitisreview