MicroRNA-23b and microRNA-27b plus flutamide treatment enhances apoptosis rate and decreases CCNG1 expression in a castration-resistant prostate cancer cell line

MicroRNA-23b and microRNA-27b plus flutamide treatment enhances apoptosis rate and decreases CCNG1 expression in a castration-resistant prostate cancer cell line

The acquisition of a castration-resistant prostate cancer phenotype by prostate cancer cells is the alteration that has the worst prognosis for patients. The aim of this study was to evaluate the role of the microRNAs-23b/-27b as well as the possible CCNG1 target gene in tissue samples from patients...

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Main Authors: Ruan CA Pimenta, Nayara I Viana, Gabriela Q Amaral, Rubens Park, Denis R Morais, José Pontes, Vanessa R Guimaraes, Juliana A Camargo, Kátia RM Leite, William C Nahas, Miguel Srougi, Sabrina T Reis
Format: Article
Language:English
Published: SAGE Publishing 2018-11-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428318803011
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