Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated Autoimmunity

A 63-year-old African-American female with history of sarcoidosis (lymph node biopsy proven) and cocaine abuse for 8 years was referred to us because of new floater. Her ocular history was unremarkable except for vague complaints of visual disturbance during a hospital admission in 2016. On presenta...

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Main Authors: Ramak Roohipourmoallai, Samaneh Davoudi, Seyed Majid Hosseinian Benvidi, Siva S. R. Iyer
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2021/9923260
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author Ramak Roohipourmoallai
Samaneh Davoudi
Seyed Majid Hosseinian Benvidi
Siva S. R. Iyer
author_facet Ramak Roohipourmoallai
Samaneh Davoudi
Seyed Majid Hosseinian Benvidi
Siva S. R. Iyer
author_sort Ramak Roohipourmoallai
collection DOAJ
description A 63-year-old African-American female with history of sarcoidosis (lymph node biopsy proven) and cocaine abuse for 8 years was referred to us because of new floater. Her ocular history was unremarkable except for vague complaints of visual disturbance during a hospital admission in 2016. On presentation, her visual acuity was 20/400 in the right eye and 20/30 in the left eye. Dilated fundus exam and multimodal imaging showed thick epiretinal membrane (ERM) superior to optic nerve head causing a lamellar macular hole and intra retinal edema in the right eye, a full thickness macular hole, and peripheral neovascularization in the left eye. Peripheral vasculitis was appreciated in both eyes and peripheral neovascularization in the left eye on fluorescein angiography. The patient underwent laser therapy, and the new vessels regressed in the left eye without any changes in systemic medications. Multiple factors may contribute to retinal vasculitis and neovascularization including sarcoidosis, cocaine abuse, and other undiagnosed systemic vasculitis, which makes this case a mystery.
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publishDate 2021-01-01
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-e66260b66d4c43f197e9d72b235e59562025-08-20T03:26:00ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/99232609923260Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated AutoimmunityRamak Roohipourmoallai0Samaneh Davoudi1Seyed Majid Hosseinian Benvidi2Siva S. R. Iyer3Department of Ophthalmology, University Of Florida, USADepartment of Ophthalmology, University Of Florida, USADepartment of Internal Medicine, University of Florida, USADepartment of Ophthalmology, University Of Florida, USAA 63-year-old African-American female with history of sarcoidosis (lymph node biopsy proven) and cocaine abuse for 8 years was referred to us because of new floater. Her ocular history was unremarkable except for vague complaints of visual disturbance during a hospital admission in 2016. On presentation, her visual acuity was 20/400 in the right eye and 20/30 in the left eye. Dilated fundus exam and multimodal imaging showed thick epiretinal membrane (ERM) superior to optic nerve head causing a lamellar macular hole and intra retinal edema in the right eye, a full thickness macular hole, and peripheral neovascularization in the left eye. Peripheral vasculitis was appreciated in both eyes and peripheral neovascularization in the left eye on fluorescein angiography. The patient underwent laser therapy, and the new vessels regressed in the left eye without any changes in systemic medications. Multiple factors may contribute to retinal vasculitis and neovascularization including sarcoidosis, cocaine abuse, and other undiagnosed systemic vasculitis, which makes this case a mystery.http://dx.doi.org/10.1155/2021/9923260
spellingShingle Ramak Roohipourmoallai
Samaneh Davoudi
Seyed Majid Hosseinian Benvidi
Siva S. R. Iyer
Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated Autoimmunity
Case Reports in Ophthalmological Medicine
title Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated Autoimmunity
title_full Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated Autoimmunity
title_fullStr Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated Autoimmunity
title_full_unstemmed Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated Autoimmunity
title_short Peripheral Retinal Neovascularization in a Patient with Sarcoidosis and Cocaine-Associated Autoimmunity
title_sort peripheral retinal neovascularization in a patient with sarcoidosis and cocaine associated autoimmunity
url http://dx.doi.org/10.1155/2021/9923260
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AT seyedmajidhosseinianbenvidi peripheralretinalneovascularizationinapatientwithsarcoidosisandcocaineassociatedautoimmunity
AT sivasriyer peripheralretinalneovascularizationinapatientwithsarcoidosisandcocaineassociatedautoimmunity