Possibilities of a biobank for serological monitoring of infectious morbidity
Currently, monitoring infectious morbidity, control and forecasting the epidemic process is a topical health problem.Aim. To analyze the capabilities of the biobank for serological monitoring of infectious diseases using the Epstein- Barr virus (EBV), which is associated with infectious mononucleosi...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2023-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3693 |
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| author | O. A. Svitich V. V. Zverev T. V. Solomay T. A. Semenenko A. V. Nozdracheva T. P. Gotvyanskaya |
| author_facet | O. A. Svitich V. V. Zverev T. V. Solomay T. A. Semenenko A. V. Nozdracheva T. P. Gotvyanskaya |
| author_sort | O. A. Svitich |
| collection | DOAJ |
| description | Currently, monitoring infectious morbidity, control and forecasting the epidemic process is a topical health problem.Aim. To analyze the capabilities of the biobank for serological monitoring of infectious diseases using the Epstein- Barr virus (EBV), which is associated with infectious mononucleosis, as well as somatic pathology, including cancer.Material and methods. Using the quantitative enzyme- linked immunosorbent assay for specific antibodies to various EBV proteins, we studied blood serum samples from healthy individuals (2010, 2016, 2019, 2020, 2021 and 2022) from the collection of the N. F. Gamaleya National Center of Epidemiology and Microbiology.Results. For the first time, the intensity of EBV epidemic process among apparently healthy adult residents of the capital was assessed using samples of biological material and a biobank information database. At the time of examination, 0,8% of individuals were not infected with EBV, and 9,4% suffered reactivation of a chronic infection. There were no significant changes in detection rate of markers over the years.Conclusion. Certified collections of blood sera can be effectively used to study population immunity, the prevalence of individual infections, population protection nationwide, etc. |
| format | Article |
| id | doaj-art-e660d6ced24a415da5498c4498405b89 |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2023-12-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-e660d6ced24a415da5498c4498405b892025-08-20T02:59:15Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252023-12-01221110.15829/1728-8800-2023-36932795Possibilities of a biobank for serological monitoring of infectious morbidityO. A. Svitich0V. V. Zverev1T. V. Solomay2T. A. Semenenko3A. V. Nozdracheva4T. P. Gotvyanskaya5I.I. Mechnikov Research Institute of Vaccines and SeraI.I. Mechnikov Research Institute of Vaccines and SeraI.I. Mechnikov Research Institute of Vaccines and SeraN.F. Gamaleya National Center of Epidemiology and MicrobiologyN.F. Gamaleya National Center of Epidemiology and MicrobiologyN.F. Gamaleya National Center of Epidemiology and MicrobiologyCurrently, monitoring infectious morbidity, control and forecasting the epidemic process is a topical health problem.Aim. To analyze the capabilities of the biobank for serological monitoring of infectious diseases using the Epstein- Barr virus (EBV), which is associated with infectious mononucleosis, as well as somatic pathology, including cancer.Material and methods. Using the quantitative enzyme- linked immunosorbent assay for specific antibodies to various EBV proteins, we studied blood serum samples from healthy individuals (2010, 2016, 2019, 2020, 2021 and 2022) from the collection of the N. F. Gamaleya National Center of Epidemiology and Microbiology.Results. For the first time, the intensity of EBV epidemic process among apparently healthy adult residents of the capital was assessed using samples of biological material and a biobank information database. At the time of examination, 0,8% of individuals were not infected with EBV, and 9,4% suffered reactivation of a chronic infection. There were no significant changes in detection rate of markers over the years.Conclusion. Certified collections of blood sera can be effectively used to study population immunity, the prevalence of individual infections, population protection nationwide, etc.https://cardiovascular.elpub.ru/jour/article/view/3693biobankblood serum samplesserological monitoringinfectious diseasesepstein- barr virusherd immunity |
| spellingShingle | O. A. Svitich V. V. Zverev T. V. Solomay T. A. Semenenko A. V. Nozdracheva T. P. Gotvyanskaya Possibilities of a biobank for serological monitoring of infectious morbidity Кардиоваскулярная терапия и профилактика biobank blood serum samples serological monitoring infectious diseases epstein- barr virus herd immunity |
| title | Possibilities of a biobank for serological monitoring of infectious morbidity |
| title_full | Possibilities of a biobank for serological monitoring of infectious morbidity |
| title_fullStr | Possibilities of a biobank for serological monitoring of infectious morbidity |
| title_full_unstemmed | Possibilities of a biobank for serological monitoring of infectious morbidity |
| title_short | Possibilities of a biobank for serological monitoring of infectious morbidity |
| title_sort | possibilities of a biobank for serological monitoring of infectious morbidity |
| topic | biobank blood serum samples serological monitoring infectious diseases epstein- barr virus herd immunity |
| url | https://cardiovascular.elpub.ru/jour/article/view/3693 |
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