Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi Arabia

Background: The most prevalent type of inherited intellectual disability worldwide is Down syndrome. Prenatal testing can determine the possibility of a pregnant woman giving birth to an infant with Down’s. Many invasive interventions help with early diagnosis of Down’s. Although high-risk pregnanci...

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Main Authors: Nedaa Mohammed Bahkali, Ghaida Abdullah Eissa, Abdulaziz Mohammed Bashar Shaheen, Abdullah Mohammed Sanedi, Duaa Mohammed Bahkali
Format: Article
Language:English
Published: IMR Press 2023-10-01
Series:Clinical and Experimental Obstetrics & Gynecology
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Online Access:https://www.imrpress.com/journal/CEOG/50/10/10.31083/j.ceog5010220
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author Nedaa Mohammed Bahkali
Ghaida Abdullah Eissa
Abdulaziz Mohammed Bashar Shaheen
Abdullah Mohammed Sanedi
Duaa Mohammed Bahkali
author_facet Nedaa Mohammed Bahkali
Ghaida Abdullah Eissa
Abdulaziz Mohammed Bashar Shaheen
Abdullah Mohammed Sanedi
Duaa Mohammed Bahkali
author_sort Nedaa Mohammed Bahkali
collection DOAJ
description Background: The most prevalent type of inherited intellectual disability worldwide is Down syndrome. Prenatal testing can determine the possibility of a pregnant woman giving birth to an infant with Down’s. Many invasive interventions help with early diagnosis of Down’s. Although high-risk pregnancies should be offered invasive prenatal diagnosis, the International Society for Prenatal Diagnosis encourages non-invasive prenatal screening testing (NIPT) as a primary screening test for all pregnant women, regardless of risk. The present study aimed to determine the knowledge and attitude regarding NIPT among Saudi Arabian women. Methods: This cross-sectional study involving 1028 participants living in Saudi Arabia was conducted from February to March 2023, using a re-designed questionnaire shared among women with pregnancy history. The questionnaire assessed their knowledge, attitudes, and beliefs regarding NIPT. Results: Only 14.8% of our respondents had undergone NIPT; the most common indication was a recommendation from their healthcare provider (41.7%). About 3.4% of the respondents had given birth to a child with Down syndrome, and 22% had relatives with chromosomal abnormalities or genetic diseases. Surprisingly, only 22.3% of the respondents had previously heard about NIPT. The mean knowledge score about NIPT was 2.82 ± 1.89. The mean knowledge score was found to be significantly higher among females who had undergone NIPT, were aged <30, and had high school education. Conclusions: Most Saudi Arabian women have poor knowledge about NIPT and a positive attitude toward it. Thus, the suggestion is to raise awareness about NIPT use, indications, prices, and possible complications.
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spelling doaj-art-e65a4686b1484108a68b53ecc05d0bbc2025-08-20T02:04:05ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632023-10-01501022010.31083/j.ceog5010220S0390-6663(23)02199-1Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi ArabiaNedaa Mohammed Bahkali0Ghaida Abdullah Eissa1Abdulaziz Mohammed Bashar Shaheen2Abdullah Mohammed Sanedi3Duaa Mohammed Bahkali4Department of Obstetrics and Gynecology, Faculty of Medicine, King Abdul-aziz University, 25732 Jeddah, Saudi ArabiaFaculty of Medicine, King Abdul-aziz University, 25732 Jeddah, Saudi ArabiaFaculty of Medicine, King Abdul-aziz University, 25732 Jeddah, Saudi ArabiaFaculty of Medicine, King Abdul-aziz University, 25732 Jeddah, Saudi ArabiaDepartment of Obstetrics and Gynecology, Faculty of Medicine, King Abdul-aziz University, 25732 Jeddah, Saudi ArabiaBackground: The most prevalent type of inherited intellectual disability worldwide is Down syndrome. Prenatal testing can determine the possibility of a pregnant woman giving birth to an infant with Down’s. Many invasive interventions help with early diagnosis of Down’s. Although high-risk pregnancies should be offered invasive prenatal diagnosis, the International Society for Prenatal Diagnosis encourages non-invasive prenatal screening testing (NIPT) as a primary screening test for all pregnant women, regardless of risk. The present study aimed to determine the knowledge and attitude regarding NIPT among Saudi Arabian women. Methods: This cross-sectional study involving 1028 participants living in Saudi Arabia was conducted from February to March 2023, using a re-designed questionnaire shared among women with pregnancy history. The questionnaire assessed their knowledge, attitudes, and beliefs regarding NIPT. Results: Only 14.8% of our respondents had undergone NIPT; the most common indication was a recommendation from their healthcare provider (41.7%). About 3.4% of the respondents had given birth to a child with Down syndrome, and 22% had relatives with chromosomal abnormalities or genetic diseases. Surprisingly, only 22.3% of the respondents had previously heard about NIPT. The mean knowledge score about NIPT was 2.82 ± 1.89. The mean knowledge score was found to be significantly higher among females who had undergone NIPT, were aged <30, and had high school education. Conclusions: Most Saudi Arabian women have poor knowledge about NIPT and a positive attitude toward it. Thus, the suggestion is to raise awareness about NIPT use, indications, prices, and possible complications.https://www.imrpress.com/journal/CEOG/50/10/10.31083/j.ceog5010220noninvasive prenatal testingprenatal investigationsmaternal fetal healthdown syndrome
spellingShingle Nedaa Mohammed Bahkali
Ghaida Abdullah Eissa
Abdulaziz Mohammed Bashar Shaheen
Abdullah Mohammed Sanedi
Duaa Mohammed Bahkali
Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi Arabia
Clinical and Experimental Obstetrics & Gynecology
noninvasive prenatal testing
prenatal investigations
maternal fetal health
down syndrome
title Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi Arabia
title_full Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi Arabia
title_fullStr Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi Arabia
title_full_unstemmed Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi Arabia
title_short Knowledge and Attitude Regarding Non-Invasive Prenatal Testing (NIPT) among Women: A Cross-Sectional Study in Saudi Arabia
title_sort knowledge and attitude regarding non invasive prenatal testing nipt among women a cross sectional study in saudi arabia
topic noninvasive prenatal testing
prenatal investigations
maternal fetal health
down syndrome
url https://www.imrpress.com/journal/CEOG/50/10/10.31083/j.ceog5010220
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