Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor

A 23-year-old man with multiple endocrine neoplasia type 1 (MEN 1) with pancreatic tail masses and Cushing syndrome (status after transsphenoidal adenomectomy) presented with a slow-growing, asymptomatic right lower lung lobe mass confirmed to be an atypical carcinoid tumor by pathologic staging fol...

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Main Authors: Ramtin Talebi, Charalambos C. Solomides, Nathaniel R. Evans, Gregory C. Kane
Format: Article
Language:English
Published: American College of Physicians 2025-06-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.0890
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author Ramtin Talebi
Charalambos C. Solomides
Nathaniel R. Evans
Gregory C. Kane
author_facet Ramtin Talebi
Charalambos C. Solomides
Nathaniel R. Evans
Gregory C. Kane
author_sort Ramtin Talebi
collection DOAJ
description A 23-year-old man with multiple endocrine neoplasia type 1 (MEN 1) with pancreatic tail masses and Cushing syndrome (status after transsphenoidal adenomectomy) presented with a slow-growing, asymptomatic right lower lung lobe mass confirmed to be an atypical carcinoid tumor by pathologic staging following successful basilar segmentectomy with mediastinal lymphadenectomy. Pulmonary carcinoid tumor (PCT) is a rare neoplasm in patients with MEN 1, but there is limited data on trends in atypical versus typical carcinoid tumors in these patients. This case emphasizes the need to characterize these trends given the implications for metastatic potential and 5-year survival, which can help guide screening recommendations in these patients.
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issn 2767-7664
language English
publishDate 2025-06-01
publisher American College of Physicians
record_format Article
series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-e6536ff75e8245e2bb59354ef81a2bde2025-08-20T02:40:27ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-06-014610.7326/aimcc.2023.0890Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid TumorRamtin Talebi0Charalambos C. Solomides1Nathaniel R. Evans2Gregory C. Kane31Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania2Department of Pathology, Thomas Jefferson University, Philadelphia, Pennsylvania3The Jane and Leonard Korman Respiratory Institute, Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania3The Jane and Leonard Korman Respiratory Institute, Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, PennsylvaniaA 23-year-old man with multiple endocrine neoplasia type 1 (MEN 1) with pancreatic tail masses and Cushing syndrome (status after transsphenoidal adenomectomy) presented with a slow-growing, asymptomatic right lower lung lobe mass confirmed to be an atypical carcinoid tumor by pathologic staging following successful basilar segmentectomy with mediastinal lymphadenectomy. Pulmonary carcinoid tumor (PCT) is a rare neoplasm in patients with MEN 1, but there is limited data on trends in atypical versus typical carcinoid tumors in these patients. This case emphasizes the need to characterize these trends given the implications for metastatic potential and 5-year survival, which can help guide screening recommendations in these patients.https://www.acpjournals.org/doi/10.7326/aimcc.2023.0890
spellingShingle Ramtin Talebi
Charalambos C. Solomides
Nathaniel R. Evans
Gregory C. Kane
Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor
Annals of Internal Medicine: Clinical Cases
title Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor
title_full Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor
title_fullStr Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor
title_full_unstemmed Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor
title_short Slow-Growing Lung Mass in a Patient With Multiple Endocrine Neoplasia Type I: Consider Carcinoid Tumor
title_sort slow growing lung mass in a patient with multiple endocrine neoplasia type i consider carcinoid tumor
url https://www.acpjournals.org/doi/10.7326/aimcc.2023.0890
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AT nathanielrevans slowgrowinglungmassinapatientwithmultipleendocrineneoplasiatypeiconsidercarcinoidtumor
AT gregoryckane slowgrowinglungmassinapatientwithmultipleendocrineneoplasiatypeiconsidercarcinoidtumor