Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review

Chronic inflammatory demyelinating polyneuropathy (CIDP) following viral infections and influenza vaccination has been well documented. However, there have been no confirmed natural influenza A infections leading to development of CIDP. Therefore, we present the case of a 6-year-old male who develop...

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Main Authors: Emily Grew, Garrett Gianneschi, Janet Elgallab
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/crnm/8840308
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author Emily Grew
Garrett Gianneschi
Janet Elgallab
author_facet Emily Grew
Garrett Gianneschi
Janet Elgallab
author_sort Emily Grew
collection DOAJ
description Chronic inflammatory demyelinating polyneuropathy (CIDP) following viral infections and influenza vaccination has been well documented. However, there have been no confirmed natural influenza A infections leading to development of CIDP. Therefore, we present the case of a 6-year-old male who developed CIDP following a confirmed influenza A infection. Initially presenting with typical flu-like symptoms, the patient experienced a gradual onset of gait instability and leg weakness approximately 1 month later. Despite initial improvement with intravenous immunoglobulin therapy following a diagnosis of Guillain–Barré syndrome, his symptoms relapsed, including lower extremity weakness, incontinence, and sensory loss. Electromyography confirmed a demyelinating polyneuropathy, leading to a diagnosis of CIDP.
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spelling doaj-art-e64fbf69f9dc40b1a94242b28b25648b2025-08-20T02:57:32ZengWileyCase Reports in Neurological Medicine2090-66762025-01-01202510.1155/crnm/8840308Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature ReviewEmily Grew0Garrett Gianneschi1Janet Elgallab2Department of PediatricsDepartment of NeurologyDepartment of NeurologyChronic inflammatory demyelinating polyneuropathy (CIDP) following viral infections and influenza vaccination has been well documented. However, there have been no confirmed natural influenza A infections leading to development of CIDP. Therefore, we present the case of a 6-year-old male who developed CIDP following a confirmed influenza A infection. Initially presenting with typical flu-like symptoms, the patient experienced a gradual onset of gait instability and leg weakness approximately 1 month later. Despite initial improvement with intravenous immunoglobulin therapy following a diagnosis of Guillain–Barré syndrome, his symptoms relapsed, including lower extremity weakness, incontinence, and sensory loss. Electromyography confirmed a demyelinating polyneuropathy, leading to a diagnosis of CIDP.http://dx.doi.org/10.1155/crnm/8840308
spellingShingle Emily Grew
Garrett Gianneschi
Janet Elgallab
Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
Case Reports in Neurological Medicine
title Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
title_full Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
title_fullStr Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
title_full_unstemmed Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
title_short Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
title_sort chronic inflammatory demyelinating polyneuropathy following natural influenza a infection in a pediatric patient a case report and literature review
url http://dx.doi.org/10.1155/crnm/8840308
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AT garrettgianneschi chronicinflammatorydemyelinatingpolyneuropathyfollowingnaturalinfluenzaainfectioninapediatricpatientacasereportandliteraturereview
AT janetelgallab chronicinflammatorydemyelinatingpolyneuropathyfollowingnaturalinfluenzaainfectioninapediatricpatientacasereportandliteraturereview