A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, Nigeria
Conclusion: HU modulates the D-dimer and TAT levels of children living with SCA toward the normal reference range, thus reducing the risk of hypercoagulability and associated sequelae. Therefore, continuous advocacy for HU use should entail close monitoring of adverse effects.
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Advances in Hematology |
| Online Access: | http://dx.doi.org/10.1155/ah/5002373 |
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| author | Blessing E. Kene-Udemezue Abideen O. Salako Adeseye M. Akinsete Oluwatosin O. Odubela Titilope A. Adeyemo |
| author_facet | Blessing E. Kene-Udemezue Abideen O. Salako Adeseye M. Akinsete Oluwatosin O. Odubela Titilope A. Adeyemo |
| author_sort | Blessing E. Kene-Udemezue |
| collection | DOAJ |
| description | Conclusion: HU modulates the D-dimer and TAT levels of children living with SCA toward the normal reference range, thus reducing the risk of hypercoagulability and associated sequelae. Therefore, continuous advocacy for HU use should entail close monitoring of adverse effects. |
| format | Article |
| id | doaj-art-e64d010dcc7a459a93a7a151d42550ca |
| institution | DOAJ |
| issn | 1687-9112 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Hematology |
| spelling | doaj-art-e64d010dcc7a459a93a7a151d42550ca2025-08-20T02:51:43ZengWileyAdvances in Hematology1687-91122024-01-01202410.1155/ah/5002373A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, NigeriaBlessing E. Kene-Udemezue0Abideen O. Salako1Adeseye M. Akinsete2Oluwatosin O. Odubela3Titilope A. Adeyemo4Department of PaediatricsClinical Sciences DepartmentDepartment of PaediatricsClinical Sciences DepartmentDepartment of PaediatricsConclusion: HU modulates the D-dimer and TAT levels of children living with SCA toward the normal reference range, thus reducing the risk of hypercoagulability and associated sequelae. Therefore, continuous advocacy for HU use should entail close monitoring of adverse effects.http://dx.doi.org/10.1155/ah/5002373 |
| spellingShingle | Blessing E. Kene-Udemezue Abideen O. Salako Adeseye M. Akinsete Oluwatosin O. Odubela Titilope A. Adeyemo A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, Nigeria Advances in Hematology |
| title | A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, Nigeria |
| title_full | A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, Nigeria |
| title_fullStr | A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, Nigeria |
| title_full_unstemmed | A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, Nigeria |
| title_short | A Comparative Analysis of Hydroxyurea Treatment on Coagulation Profile Among Sickle Cell Anaemia Children in Lagos, Nigeria |
| title_sort | comparative analysis of hydroxyurea treatment on coagulation profile among sickle cell anaemia children in lagos nigeria |
| url | http://dx.doi.org/10.1155/ah/5002373 |
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